Kalinina A M, Chazova L V
Ter Arkh. 1998;70(1):8-12.
Assessment of the probability of decreasing cardiovascular mortality by detecting and treating coronary patients and patients with arterial hypertension and correcting the risk factors.
A prospective ten-year registration of the mortality of the male population aged 40 to 59 years was carried out at a Moscow territory with two health centers. The subjects were routinely screened for coronary disease, arterial hypertension, hypercholesterolemia, excess body weight, tobacco smoking, insufficient exercise. During the first five years of the follow-up they were involved in treatment and prophylaxis measures varying in activity and direction (the two health centers were specialized in prevention and common treatment).
Multifactorial prophylactic intervention helped delay untimely death in all the population examined, mainly due to detection of cardiovascular diseases. The life prognosis was improved most appreciably in the cases when the levels of risk factors were decreased due to multifactorial prevention in comparison with the life prognosis for subjects with a similar decrease of risk factors but without prophylactic intervention.
通过检测和治疗冠心病患者、动脉高血压患者以及纠正危险因素，评估降低心血管死亡率的可能性。
在莫斯科地区的两个健康中心对40至59岁男性人群进行了为期十年的前瞻性死亡率登记。对受试者进行冠心病、动脉高血压、高胆固醇血症、体重超标、吸烟、运动不足的常规筛查。在随访的前五年中，他们参与了活动和方向各异的治疗和预防措施（两个健康中心分别专门从事预防和普通治疗）。
多因素预防性干预有助于延缓所有受检人群的过早死亡，主要是由于心血管疾病的检测。与危险因素有类似降低但未进行预防性干预的受试者的生命预后相比，在因多因素预防而使危险因素水平降低的情况下，生命预后改善最为明显。
