[The role of persistence factors in the forming of a microbial biocenosis in the nasal mucosa in staphylococcal bacteria carriers].

The microbial biocenosis of the nasal mucosa under normal conditions and in cases of Staphylococcus aureus carriership was studied, taking into account the biological properties of symbionts in 159 persons. In S. aureus carriers the dysbiotic state of the intranasal microflora was established: the decrease of the index of total microbial contamination, the index of contamination with obligate coccal microflora and the index of specific diversity. The factors of the persistence and antagonism of dysbiotic microflora contribute to the mechanism of the development of dysbiosis. In the biocenosis of the carriers obligate microflora strains (Corynebacterium, Micrococcus and coagulase-negative staphylococci) with more pronounced interspecific antagonism or bacteriocinogeny were dominant.