金黄色葡萄球菌鼻腔定植中的人为因素。
Human factor in Staphylococcus aureus nasal carriage.
作者信息
Nouwen Jan, Boelens Hélène, van Belkum Alex, Verbrugh Henri
机构信息
Erasmus MC, Department of Medical Microbiology & Infectious Diseases, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
出版信息
Infect Immun. 2004 Nov;72(11):6685-8. doi: 10.1128/IAI.72.11.6685-6688.2004.
Abstract
Persistent nasal carriers and noncarriers of Staphylococcus aureus were inoculated with a mixture of different S. aureus strains. The majority of noncarriers and nearly all persistent carriers returned to their original carrier state after artificial inoculation. Furthermore, the majority of persistent carriers tested positive again for their original resident strain. Using a human nasal inoculation model, we here demonstrate that the human factor is an important determinant of S. aureus nasal carriage.
摘要
用不同金黄色葡萄球菌菌株的混合物对持续性鼻腔金黄色葡萄球菌携带者和非携带者进行接种。大多数非携带者以及几乎所有持续性携带者在人工接种后恢复到原来的携带状态。此外，大多数持续性携带者对其原来的常驻菌株再次检测呈阳性。我们在此利用人类鼻腔接种模型证明，人类因素是金黄色葡萄球菌鼻腔携带的一个重要决定因素。
相似文献
1
Human factor in Staphylococcus aureus nasal carriage.金黄色葡萄球菌鼻腔定植中的人为因素。
Infect Immun. 2004 Nov;72(11):6685-8. doi: 10.1128/IAI.72.11.6685-6688.2004.
2
Reclassification of Staphylococcus aureus nasal carriage types.金黄色葡萄球菌鼻腔携带类型的重新分类
J Infect Dis. 2009 Jun 15;199(12):1820-6. doi: 10.1086/599119.
3
Effect of mupirocin treatment on nasal, pharyngeal, and perineal carriage of Staphylococcus aureus in healthy adults.莫匹罗星治疗对健康成年人金黄色葡萄球菌鼻腔、咽部和会阴部携带情况的影响。
Antimicrob Agents Chemother. 2005 Apr;49(4):1465-7. doi: 10.1128/AAC.49.4.1465-1467.2005.
4
What determines nasal carriage of Staphylococcus aureus?是什么决定了金黄色葡萄球菌的鼻腔携带情况？
Trends Microbiol. 2001 Dec;9(12):605-10. doi: 10.1016/s0966-842x(01)02254-5.
5
Typing of Staphylococcus aureus colonising human nasal carriers by pulsed-field gel electrophoresis.通过脉冲场凝胶电泳对定植于人类鼻腔的金黄色葡萄球菌进行分型
J Med Microbiol. 1995 Feb;42(2):127-32. doi: 10.1099/00222615-42-2-127.
6
7
Prevalence of cutaneous bacterial infections and nasal carriage of Staphylococcus aureus in recipients of renal transplants.肾移植受者皮肤细菌感染及金黄色葡萄球菌鼻腔携带情况的患病率
Clin Exp Dermatol. 2009 Mar;34(2):156-60. doi: 10.1111/j.1365-2230.2008.02822.x.
8
The turnover of strains in intermittent and persistent nasal carriers of Staphylococcus aureus.金黄色葡萄球菌间歇性和持续性鼻腔携带者的菌株更替。
J Infect. 2016 Mar;72(3):295-301. doi: 10.1016/j.jinf.2015.12.010. Epub 2015 Dec 24.
9
Suppression of innate immunity by a nasal carriage strain of Staphylococcus aureus increases its colonization on nasal epithelium.金黄色葡萄球菌鼻腔携带菌株对固有免疫的抑制作用增强了其在鼻上皮的定植。
Immunology. 2007 Sep;122(1):80-9. doi: 10.1111/j.1365-2567.2007.02615.x. Epub 2007 Apr 30.
10
Persistent Staphylococcus aureus nasal colonization in ambulatory human immunodeficiency virus-infected patients in Nigeria: Risk factors and molecular features.尼日利亚门诊人类免疫缺陷病毒感染患者中金黄色葡萄球菌鼻腔定植的持久性：危险因素和分子特征。
J Microbiol Immunol Infect. 2016 Dec;49(6):992-995. doi: 10.1016/j.jmii.2014.12.003. Epub 2014 Dec 24.
引用本文的文献
1
Bacterial infections and pathogenic situations: The case of .细菌感染与致病情况：以……为例
Virulence. 2025 Dec;16(1):2543538. doi: 10.1080/21505594.2025.2543538. Epub 2025 Aug 13.
2
Risk Identification and Mitigation of Skin and Soft Tissue Infections in Military Training Environments.军事训练环境中皮肤和软组织感染的风险识别与缓解
Trop Med Infect Dis. 2024 Dec 14;9(12):306. doi: 10.3390/tropicalmed9120306.
3
New Antibiotics for Infection: An Update from the World Association of Infectious Diseases and Immunological Disorders (WAidid) and the Italian Society of Anti-Infective Therapy (SITA).用于感染的新型抗生素：来自世界传染病与免疫紊乱协会（WAidid）和意大利抗感染治疗学会（SITA）的最新进展。
Antibiotics (Basel). 2023 Apr 12;12(4):742. doi: 10.3390/antibiotics12040742.
4
MRSA carriage among healthcare workers in a Vietnamese intensive care unit: a prospective cohort study.越南重症监护病房医护人员耐甲氧西林金黄色葡萄球菌携带情况：一项前瞻性队列研究。
Drug Target Insights. 2022 Dec 31;16:71-77. doi: 10.33393/dti.2022.2504. eCollection 2022 Jan-Dec.
5
Worsening Glycemia Increases the Odds of Intermittent but Not Persistent Staphylococcus aureus Nasal Carriage in Two Cohorts of Mexican American Adults.血糖恶化增加了两名墨西哥裔美国成年人队列中金黄色葡萄球菌间歇性而非持续性鼻腔携带的几率。
Microbiol Spectr. 2022 Jun 29;10(3):e0000922. doi: 10.1128/spectrum.00009-22. Epub 2022 May 18.
6
Improving mathematical modeling of interventions to prevent healthcare-associated infections by interrupting transmission or pathogens: How common modeling assumptions about colonized individuals impact intervention effectiveness estimates.通过阻断传播或病原体来改进预防医疗机构相关性感染的干预措施的数学建模：关于定植个体的常见建模假设如何影响干预效果估计。
PLoS One. 2022 Feb 28;17(2):e0264344. doi: 10.1371/journal.pone.0264344. eCollection 2022.
7
Methicillin-resistant nasal colonization in people living with HIV and healthy people in Kathmandu, Nepal.尼泊尔加德满都艾滋病毒感染者和健康人群中的耐甲氧西林鼻腔定植情况。
Future Sci OA. 2021 Nov 26;8(2):FSO769. doi: 10.2144/fsoa-2021-0103. eCollection 2022 Feb.
8
Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage among patients with diabetes at the Korle Bu Teaching Hospital.科托努教学医院糖尿病患者耐甲氧西林金黄色葡萄球菌（MRSA）鼻腔携带情况。
PLoS One. 2021 Sep 17;16(9):e0257004. doi: 10.1371/journal.pone.0257004. eCollection 2021.
9
Keratitis: Incidence, Pathophysiology, Risk Factors and Novel Strategies for Treatment.角膜炎：发病率、病理生理学、危险因素及新型治疗策略
J Clin Med. 2021 Feb 13;10(4):758. doi: 10.3390/jcm10040758.
10
Recurrent microbial keratitis and endogenous site Staphylococcus aureus colonisation.复发性微生物角膜炎与内源性定植的金黄色葡萄球菌。
Sci Rep. 2020 Oct 29;10(1):18559. doi: 10.1038/s41598-020-75821-z.
本文引用的文献
1
Predicting the Staphylococcus aureus nasal carrier state: derivation and validation of a "culture rule".预测金黄色葡萄球菌鼻腔携带状态：“培养规则”的推导与验证
Clin Infect Dis. 2004 Sep 15;39(6):806-11. doi: 10.1086/423376. Epub 2004 Aug 26.
2
Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children.健康儿童中肺炎链球菌和金黄色葡萄球菌的定植情况。
Lancet. 2004 Jun 5;363(9424):1871-2. doi: 10.1016/S0140-6736(04)16357-5.
3
Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections.磷壁酸在金黄色葡萄球菌鼻腔定植中的作用，医院感染的主要危险因素。
Nat Med. 2004 Mar;10(3):243-5. doi: 10.1038/nm991. Epub 2004 Feb 1.
4
Determinants of acquisition and carriage of Staphylococcus aureus in infancy.婴儿期金黄色葡萄球菌感染与携带的决定因素
J Clin Microbiol. 2003 Dec;41(12):5718-25. doi: 10.1128/JCM.41.12.5718-5725.2003.
5
The normal flora of the nose in twins.双胞胎鼻腔的正常菌群。
Acta Leiden. 1963;32:123-33.
6
Determinants of Staphylococcus aureus nasal carriage.金黄色葡萄球菌鼻腔定植的决定因素。
Clin Diagn Lab Immunol. 2001 Nov;8(6):1064-9. doi: 10.1128/CDLI.8.6.1064-1069.2001.
7
Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group.鼻腔带菌作为金黄色葡萄球菌菌血症的一个来源。研究组。
N Engl J Med. 2001 Jan 4;344(1):11-6. doi: 10.1056/NEJM200101043440102.
8
Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state.8年后金黄色葡萄球菌鼻腔定植的随访：重新定义持续携带者状态
J Clin Microbiol. 1999 Oct;37(10):3133-40. doi: 10.1128/JCM.37.10.3133-3140.1999.
9
Innate antimicrobial activity of nasal secretions.鼻腔分泌物的固有抗菌活性。
Infect Immun. 1999 Jul;67(7):3267-75. doi: 10.1128/IAI.67.7.3267-3275.1999.
10
Clonal expansion of Staphylococcus epidermidis strains causing Hickman catheter-related infections in a hemato-oncologic department.血液肿瘤科室中引起希克曼导管相关感染的表皮葡萄球菌菌株的克隆扩增。
J Clin Microbiol. 1998 Sep;36(9):2696-702. doi: 10.1128/JCM.36.9.2696-2702.1998.
Zotero 插件