Imai T, Saito M, Matsumoto H, Ishikawa Y, Ishikawa Y, Minami R
Department of Neurology, School of Medicine, Sapporo Medical University, Japan.
Brain Dev. 1998 Jan;20(1):44-6. doi: 10.1016/s0387-7604(97)00098-3.
The purpose of this study is to elucidate the interrelation between the M and F wave characteristics of the median nerve and the grip power in patients with spinal muscular atrophy (SMA). The SMA patients showed decreased amplitudes of the M and F waves, decreased frequency of the F wave, and an increase of the F/M ratio as compared with the normative values. The F wave frequency and the amplitudes of M and F waves, which showed a significant linear correlation with each other, became lower in accordance with the decrease of grip power. The properties of M and F waves strongly correlated with the number of surviving motor neurons which would be fewer in those severely affected by SMA.
