Gralton E J, James D H, Lindsey M P
Trecare NHS Trust, Truro, Cornwall, England.
J Intellect Disabil Res. 1998 Feb;42 ( Pt 1):49-57. doi: 10.1046/j.1365-2788.1998.00097.x.
This study is a follow-up to an original survey carried out in the early 1980s of all children with an identified intellectual disability in Cornwall, England. The purpose of this second study was to review the use of antipsychotic medication in these children and to relate it to their various diagnoses. This is a relatively under-researched area, and the few comparable studies in children have not been designed to specify diagnoses, psychiatric or otherwise. A positive relationship between the diagnosis of autistic spectrum disorders in children and the use of antipsychotic medication was one of the important findings which emerged from the research. The possible reasons for this association are discussed.
本研究是对20世纪80年代初在英国康沃尔郡对所有已确诊智力残疾儿童进行的一项原始调查的后续研究。第二项研究的目的是回顾这些儿童中抗精神病药物的使用情况,并将其与他们的各种诊断联系起来。这是一个相对研究不足的领域,儿童中少数类似研究并非旨在明确诊断,无论是精神方面的还是其他方面的。儿童自闭症谱系障碍诊断与抗精神病药物使用之间的正相关关系是该研究得出的重要发现之一。文中讨论了这种关联的可能原因。