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下生殖道合并感染对宫颈癌筛查的影响。

Effect of concurrent lower genital tract infections on cervical cancer screening.

作者信息

Schwebke J R, Zajackowski M E

机构信息

Department of Health, Chicago, USA.

出版信息

Genitourin Med. 1997 Oct;73(5):383-6. doi: 10.1136/sti.73.5.383.

Abstract

BACKGROUND AND OBJECTIVES

Although women attending STD clinics are at high risk for cervical cancer, most STD programmes do not include Papanicolaou (Pap) smears in their routine screening procedures. Concerns regarding reliability of this test in a population with a high rate of active infection are often raised. The objective of this study was to analyse the associations between STD diagnosis/clinical syndromes and unsatisfactory and abnormal Pap smears.

METHODS

Retrospective analysis of Pap results and medical records from women attending an inner city STD programme.

RESULTS

Of the 1202 patients analysed, 3.2% had squamous intraepithelial lesions (SIL) and 3.5% had smears which were unsatisfactory because of the thickness of the specimen. There were no associations between STD diagnoses and SIL; however, the presence of cervical inflammation was significantly associated with SIL. Pap smears which were unsatisfactory because they were too thick were also associated with the clinical finding of cervical inflammation.

CONCLUSIONS

The presence of active infection did not preclude the detection of SIL on Pap smears. The percentage of unsatisfactory smears resulting from inflammation was low.

摘要

背景与目的

尽管前往性传播疾病(STD)诊所就诊的女性患宫颈癌的风险很高,但大多数STD项目在其常规筛查程序中并未包括巴氏涂片检查。人们经常对该检查在活动性感染率高的人群中的可靠性表示担忧。本研究的目的是分析STD诊断/临床综合征与不满意及异常巴氏涂片之间的关联。

方法

对参加市中心STD项目的女性的巴氏检查结果和病历进行回顾性分析。

结果

在分析的1202例患者中,3.2%患有鳞状上皮内病变(SIL),3.5%的涂片因标本过厚而不满意。STD诊断与SIL之间无关联;然而,宫颈炎症的存在与SIL显著相关。因涂片过厚而不满意的巴氏涂片也与宫颈炎症的临床发现相关。

结论

活动性感染的存在并不妨碍通过巴氏涂片检测到SIL。因炎症导致的不满意涂片的比例较低。

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本文引用的文献

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Cancer statistics, 1994.1994年癌症统计数据。
CA Cancer J Clin. 1994 Jan-Feb;44(1):7-26. doi: 10.3322/canjclin.44.1.7.
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The inflammatory Papanicolaou smear: what does it mean?炎性巴氏涂片:这意味着什么?
Obstet Gynecol. 1995 Sep;86(3):360-6. doi: 10.1016/0029-7844(95)00196-X.
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Missed opportunities for early diagnosis of cancer of the cervix.宫颈癌早期诊断的错失机会。
Am J Public Health. 1980 Apr;70(4):418-20. doi: 10.2105/ajph.70.4.418.
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The role of cervical cytology in the declining morbidity and mortality of cervical cancer.
Cancer. 1974 Dec;34(6):2018-27. doi: 10.1002/1097-0142(197412)34:6<2018::aid-cncr2820340621>3.0.co;2-b.

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