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人类受试者在腕部运动心理模拟过程中皮质脊髓兴奋性的调制。

Corticospinal excitability modulation during mental simulation of wrist movements in human subjects.

作者信息

Rossi S, Pasqualetti P, Tecchio F, Pauri F, Rossini P M

机构信息

IRCCS Centro S. Giovanni di Dio-F.B.F. c/o Istituto Sacro Cuore, Brescia, Italy.

出版信息

Neurosci Lett. 1998 Feb 27;243(1-3):147-51. doi: 10.1016/s0304-3940(98)00088-3.

DOI:10.1016/s0304-3940(98)00088-3
PMID:9535135
Abstract

Motor evoked potentials (MEPs) to magnetic transcranial stimulation (TCS) were simultaneously and bilaterally recorded from flexor carpi radialis (FCR) and extensor communis digitorum (ECD) muscles in seven healthy and trained subjects. Latencies and amplitudes characteristics of MEPs were investigated under the following randomised conditions: muscular and mental relaxation; mental simulation, during absolute muscular relaxation, selective flexion or extension of the right or left wrist muscles; arithmetical calculation with muscular relaxation. Unspecific, diffuse facilitatory effects on MEPs amplitude were induced by mental non motor activity (arithmetical calculation). A further specific and lateralised amplitude potentiation on the agonist muscle acting as 'prime mover' for the mentally simulated movement was consistently found in all the subjects, without significant latency changes. Inhibitory effects on antagonists were evident only in two subjects.

摘要

在7名健康且训练有素的受试者中,从桡侧腕屈肌(FCR)和指总伸肌(ECD)肌肉同时双侧记录磁刺激经颅磁刺激(TCS)诱发的运动诱发电位(MEP)。在以下随机条件下研究MEP的潜伏期和波幅特征:肌肉和精神放松;在绝对肌肉放松期间进行精神模拟,右手或左手腕部肌肉选择性屈伸;肌肉放松时进行算术计算。精神非运动活动(算术计算)对MEP波幅产生非特异性、弥漫性促进作用。在所有受试者中均始终发现,对于作为精神模拟运动“原动肌”的主动肌,其波幅进一步出现特异性和侧化增强,且潜伏期无明显变化。仅在两名受试者中观察到对拮抗肌的抑制作用。

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