Lachkar Y, Cohn H
Rothschild Eye Foundation, Paris, France.
Eye (Lond). 1997;11 ( Pt 6):810-7. doi: 10.1038/eye.1997.211.
Glaucoma is an optic neuropathy in which optic nerve changes are important in diagnosis and progression, because the visual field may remain normal even while the optic nerve is undergoing significant damage. Accurate methods to objectively document the appearance of the optic nerve are necessary. In order for an optic disc imaging system to be clinically useful for detecting change, its reproducibility must be established.
We measured the reproducibility of duplicate measurements in 59 eyes of 31 consecutive patients, grouped into glaucoma subjects (n = 29) and eyes with glaucoma (n = 30), with the 3.10 OIS Glaucoma-Scope. In order to simulate two visits on one day, sets of three optic disc images were obtained first, followed by a repeat set, and the best disc images of each (chosen by the computer) were compared.
The coefficients of variation of duplicate measurements for glaucoma suspects and patients with glaucoma were respectively: vertical cup/disc (c/d) ratio, 6.3% and 3.47%; horizontal c/d ratio, 4.61% and 2.97%; c/d area, 3.29% and 1.37%; cup area, 1.82% and 1.72%; mean position (MP) disc, 13.3% and 10.42%; MP total, 10.1% and 13.2%. For three eyes the examination was not possible (opacification of posterior capsule, miosis).
These results suggest that the 3.10 version of the OIS Glaucoma-Scope allows reproducible measurements in living eyes.
青光眼是一种视神经病变，其中视神经变化在诊断和病情进展中至关重要，因为即使视神经正遭受严重损害，视野仍可能保持正常。因此，需要准确的方法来客观记录视神经的外观。为使视盘成像系统在临床上能有效检测变化，必须确定其可重复性。
我们使用3.10 OIS青光眼镜对31例连续患者的59只眼睛进行重复测量的可重复性检测，这些眼睛分为青光眼可疑患者组（n = 29）和青光眼患者组（n = 30）。为模拟一天内的两次就诊，首先获取三组视盘图像，然后重复获取一组，比较每组中（由计算机选择）最佳的视盘图像。
青光眼可疑患者和青光眼患者重复测量的变异系数分别为：垂直杯盘（c/d）比，6.3%和3.47%；水平c/d比，4.61%和2.97%；c/d面积，3.29%和1.37%；杯面积，1.82%和1.72%；视盘平均位置（MP），13.3%和10.42%；总MP，10.1%和13.2%。有三只眼睛无法进行检查（后囊混浊、瞳孔缩小）。
这些结果表明，3.10版OIS青光眼镜能够对活体眼睛进行可重复测量。
