Irinoda T, Terashima M, Takagane A, Sasaki N, Abe K, Araya M, Nishizuka S, Yonezawa H, Nakaya T, Shimooki O, Oyama K, Ikeda K, Saito K
Department of Surgery I, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020, Japan.
Oncol Rep. 1998 May-Jun;5(3):661-6. doi: 10.3892/or.5.3.661.
This study was designed to evaluate the usefulness of carcinoembryonic antigen (CEA) and sialyl-Tn antigen (STN) levels in peritoneal washings in gastric cancer patients. At the time of laparotomy, peritoneal washings were collected from 96 gastric cancer patients and CEA and STN levels were determined. Patients with elevated CEA (100 ng/g protein) had a high incidence for peritoneal metastasis, lymph node metastasis and serosal invasion. In addition, prognosis in patients with high CEA level was significantly poorer than in those without it. The peritoneal CEA is a prognostic factor in patients with gastric cancer.
本研究旨在评估癌胚抗原（CEA）和唾液酸-Tn抗原（STN）水平在胃癌患者腹腔冲洗液中的应用价值。在剖腹手术时，收集了96例胃癌患者的腹腔冲洗液，并测定了CEA和STN水平。CEA升高（>100 ng/g蛋白）的患者发生腹膜转移、淋巴结转移和浆膜侵犯的发生率较高。此外，CEA水平高的患者预后明显比CEA水平不高的患者差。腹腔CEA是胃癌患者的一个预后因素。
