von Birgelen C, Mintz G S, de Vrey E A, Kimura T, Popma J J, Airiian S G, Leon M B, Nobuyoshi M, Serruys P W, de Feyter P J
Thoraxcenter, University Hospital Rotterdam-Dijkzigt, Netherlands.
Heart. 1998 Feb;79(2):137-42. doi: 10.1136/hrt.79.2.137.
To compare vessel, lumen, and plaque volumes in atherosclerotic coronary lesions with inadequate compensatory enlargement versus lesions with adequate compensatory enlargement.
35 angiographically significant coronary lesions were examined by intravascular ultrasound (IVUS) during motorised transducer pullback. Segments 20 mm in length were analysed using a validated automated three dimensional analysis system. IVUS was used to classify lesions as having inadequate (group I) or adequate (group II) compensatory enlargement.
There was no significant difference in quantitative angiographic measurements and the IVUS minimum lumen cross sectional area between groups I (n = 15) and II (n = 20). In group I, the vessel cross sectional area was 13.3 (3.0) mm2 at the lesion site and 14.4 (3.6) mm2 at the distal reference (p < 0.01), whereas in group II it was 17.5 (5.6) mm2 at the lesion site and 14.0 (6.0) mm2 at the distal reference (p < 0.001). Vessel and plaque cross sectional areas were significantly smaller in group I than in group II (13.3 (3.0) v 17.5 (5.6) mm2, p < 0.01; and 10.9 (2.8) v 15.2 (4.9) mm2; p < 0.005). Similarly, vessel and plaque volume were smaller in group I (291.0 (61.0) v 353.7 (110.0) mm3, and 177.5 (48.4) v 228.0 (92.8) mm3, p < 0.05 for both). Lumen areas and volumes were similar.
In lesions with inadequate compensatory enlargement, both vessel and plaque volume appear to be smaller than in lesions with adequate compensatory enlargement.
比较代偿性扩张不足的动脉粥样硬化性冠状动脉病变与代偿性扩张充分的病变的血管、管腔和斑块体积。
在电动换能器回撤过程中，通过血管内超声（IVUS）对35处血管造影显示有意义的冠状动脉病变进行检查。使用经过验证的自动三维分析系统对20毫米长的节段进行分析。IVUS用于将病变分类为代偿性扩张不足（I组）或代偿性扩张充分（II组）。
I组（n = 15）和II组（n = 20）之间在定量血管造影测量和IVUS最小管腔横截面积方面无显著差异。在I组中，病变部位的血管横截面积为13.3（3.0）平方毫米，远端参考部位为14.4（3.6）平方毫米（p < 0.01），而在II组中，病变部位为17.5（5.6）平方毫米，远端参考部位为14.0（6.0）平方毫米（p < 0.001）。I组的血管和斑块横截面积明显小于II组（13.3（3.0）对17.5（5.6）平方毫米，p < 0.01；以及10.9（2.8）对15.2（4.9）平方毫米；p < 0.005）。同样，I组的血管和斑块体积较小（291.0（61.0）对353.7（110.0）立方毫米，以及177.5（48.4）对228.0（92.8）立方毫米，两者p均< 0.05）。管腔面积和体积相似。
在代偿性扩张不足的病变中，血管和斑块体积似乎均小于代偿性扩张充分的病变。
