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采用空间滤波方法对癫痫样棘波生物磁信号进行源分析的准确性:计算机模拟

Exactness of source analysis of biomagnetic signals of epileptiform spikes by the method of spatial filtering: a computer simulation.

作者信息

Wagner H, Eiselt M, Zwiener U

机构信息

Institute of Pathological Physiology, Klinikum Friedrich Schiller Universität, Germany.

出版信息

Med Biol Eng Comput. 1997 Nov;35(6):708-14. doi: 10.1007/BF02510982.

DOI:10.1007/BF02510982
PMID:9538550
Abstract

On the basis of spatial covariance it is found that, by spatial filtering the localisation of a single dipole source, both parallel and perpendicular to the measurement plane (assuming a signal-noise ratio of 5:1), can be performed with an accuracy of < 0.5 mm. When the signal-noise ratio is increased to 30:1, the resolution of temporally independent current sources separated by 2 mm becomes practicable. This resolution study is carried out by means of a pair of unity current dipoles with the dipole distance as a varying source model parameter. The conclusions, drawn from the results of computer simulation and supported by statistical calculations, refer to the spherical model of the volume conductor of the brain.

摘要

基于空间协方差发现,通过对单个偶极子源进行空间滤波,无论是平行还是垂直于测量平面(假设信噪比为5:1),都可以在精度小于0.5毫米的情况下进行定位。当信噪比提高到30:1时,相隔2毫米的时间上独立的电流源的分辨率变得可行。该分辨率研究是通过一对单位电流偶极子进行的,偶极子间距作为变化的源模型参数。从计算机模拟结果得出并得到统计计算支持的结论,适用于大脑容积导体的球形模型。

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本文引用的文献

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Relationship between dipole parameter estimation errors and measurement conditions in magnetoencephalography.脑磁图中偶极子参数估计误差与测量条件之间的关系。
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