Laha R K, Saunders F W, Huestis W S
Can Med Assoc J. 1976 Aug 7;115(3):236-7.
Herpes simplex encephalitis in a 21-year-old man presented as a flu-like illness, followed by inappropriate behaviour, drowsiness and focal neurologic signs. Investigations indicated a lesion in the right temporal lobe. The diagnosis was confirmed by isolation of the virus from a cerebral biopsy. Pronounced clinical improvement was noted when cytosine arabinoside therapy was started in the postoperative period. This report supports the observation by some authors that cytosine arabinoside may be of value in the treatment of herpes simplex encephalitis.
一名21岁男性患单纯疱疹性脑炎，最初表现为流感样疾病，随后出现行为异常、嗜睡和局灶性神经体征。检查显示右侧颞叶有病变。通过从脑活检中分离出病毒确诊。术后开始使用阿糖胞苷治疗后，临床症状明显改善。本报告支持一些作者的观察结果，即阿糖胞苷可能对治疗单纯疱疹性脑炎有价值。
