Grüning H, Heib C, Stasche N, Gauer A, Hörmann K
HNO-Klinik, Westpfalz-Klinikum GmbH Kaiserslautern.
HNO. 1998 Jan;46(1):70-2. doi: 10.1007/s001060050201.
Isolated sarcoidosis is quite rare, causing non-specific symptoms and possibly not diagnosed because of the large number of other entities with similar presentations. We report the problems of diagnosis of isolated laryngeal sarcoidosis following a localized carcinoma. A 66-year-old patient was seen in the Westpfalz ENT Department after a Le Roux-Robert fronto-latera laryngeal resection for a pT1a N0 M0 vocal cord carcinoma following progressue dyspnea. Laryngoscopy showed laryngeal stenosis due to a neoplastic lesion. However, an epitheloid granulomatosis was found on histopathology with no evidence for recurrent carcinoma. After exclusion of other processes and systemic disease, the diagnosis of isolated laryngeal sarcoidosis was made and long-term corticoid medication was administered, resulting in a rapid regression of the laryngeal stenosis.
孤立性结节病相当罕见，会引起非特异性症状，并且可能由于大量具有相似表现的其他疾病而未被诊断出来。我们报告了一例继局限性癌之后孤立性喉结节病的诊断问题。一名66岁患者因进行性呼吸困难在接受了Le Roux-Robert额侧喉切除术后，因pT1a N0 M0声带癌被送至普法尔茨西部耳鼻喉科。喉镜检查显示因肿瘤病变导致喉狭窄。然而，组织病理学发现上皮样肉芽肿，无复发性癌的证据。在排除其他病变和全身性疾病后，做出了孤立性喉结节病的诊断，并给予长期皮质类固醇药物治疗，导致喉狭窄迅速消退。
