Department of Otorhinolaryngology/Head and Neck Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
J Voice. 2013 Sep;27(5):647-9. doi: 10.1016/j.jvoice.2013.03.010. Epub 2013 May 17.
Isolated laryngeal sarcoidosis is a very rare disease. In most cases, it will present as a supraglottic pale edematous swelling. In our case, the patient presented with hoarseness and dyspnea during exertion. Laryngeal examination did show not only supraglottic edema but also prominent subglottic swelling and edematous true vocal folds. Histology showed noncaseating granulomas. After excluding other causes and localizations, the patient was diagnosed with laryngeal sarcoidosis and treated with systemic corticosteroid with good result. We describe our case of isolated transglottic sarcoidosis and discuss the disease, its presentation, diagnosis, and therapeutic options.
孤立性喉结节病是一种非常罕见的疾病。在大多数情况下，它会表现为声门上苍白水肿性肿胀。在我们的病例中，患者在用力时出现声音嘶哑和呼吸困难。喉部检查不仅显示声门上水肿，还显示明显的声门下肿胀和水肿性真声带。组织学显示非干酪样肉芽肿。在排除其他原因和定位后，患者被诊断为喉结节病，并接受全身皮质类固醇治疗，效果良好。我们描述了一例孤立性跨声门结节病，并讨论了该病的表现、诊断和治疗选择。
