Fraser R S, Stobey J, Rossall R E, Dvorkin J, Taylor R F
Can Med Assoc J. 1976 Sep 4;115(5):415-7,434.
Thirty-six patients, 19 men and 17 women, presented at age 18 or older between 1952 and 1974 with coarctation of the aorta. Of the 14 (39%) who had associated cardiovascular disease, 12 had aortic stenosis or insufficiency or both. Three patients had infections-two, endocarditis (aortic valve) and one, endarteritis. Three of the seven patients who did not undergo an operation are alive, two at more than 50 years of age. Five patients had myocardial infarctions, two at 35 years of age. Twenty-nine (80%) had operations; in eight instances the patient was over age 40. All 18 patients undergoing repair of isolated coarctation survived, while only 7 of the 11 patients with associated cardiovascular lesions who underwent repair recovered. Aortic valvular disease and myocardial infarction are serious complicating factors in coarctation of the aorta.
1952年至1974年间，36例年龄在18岁及以上的患者因主动脉缩窄前来就诊，其中男性19例，女性17例。在伴有心血管疾病的14例（39%）患者中，12例患有主动脉瓣狭窄或关闭不全或两者兼有。3例患者发生感染，2例为心内膜炎（主动脉瓣），1例为动脉内膜炎。7例未接受手术的患者中有3例存活，其中2例年龄超过50岁。5例患者发生心肌梗死，2例年龄为35岁。29例（80%）患者接受了手术，8例患者年龄超过40岁。所有18例接受单纯主动脉缩窄修复术的患者均存活，而11例伴有心血管病变并接受修复术的患者中只有7例康复。主动脉瓣疾病和心肌梗死是主动脉缩窄的严重并发症因素。
