The "best" of cholesterols, the "worst" of cholesterols: a tale of two receptors.
作者信息
Krieger M
机构信息
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
出版信息
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4077-80. doi: 10.1073/pnas.95.8.4077.
Abstract
摘要
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The "best" of cholesterols, the "worst" of cholesterols: a tale of two receptors.胆固醇的“最佳”与“最差”：两种受体的故事
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本文引用的文献
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Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis.高密度脂蛋白受体SR-BI在小鼠胚胎发育过程中的时空表达模式。
J Lipid Res. 1998 Mar;39(3):495-508.
2
Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol.靶向突变揭示了SR-BI在肝脏选择性摄取高密度脂蛋白胆固醇中的核心作用。
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4619-24. doi: 10.1073/pnas.95.8.4619.
3
Characterization and chromosomal localization of rat scavenger receptor class B type I, a high density lipoprotein receptor with a putative leucine zipper domain and peroxisomal targeting sequence.大鼠I型B类清道夫受体的特性及染色体定位，一种具有假定亮氨酸拉链结构域和过氧化物酶体靶向序列的高密度脂蛋白受体。
Endocrinology. 1998 Jan;139(1):72-80. doi: 10.1210/endo.139.1.5666.
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CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins.CLA-1是一种85千道尔顿的质膜糖蛋白，它作为天然（高密度脂蛋白、低密度脂蛋白和极低密度脂蛋白）和修饰（氧化低密度脂蛋白和乙酰化低密度脂蛋白）脂蛋白的高亲和力受体发挥作用。
Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2341-9. doi: 10.1161/01.atv.17.11.2341.
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Sequence of the bovine HDL-receptor (SR-BI) cDNA and changes in receptor mRNA expression during granulosa cell luteinization in vivo and in vitro.牛高密度脂蛋白受体（SR-BI）cDNA序列以及体内和体外颗粒细胞黄体化过程中受体mRNA表达的变化
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Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells.I型清道夫受体B类（SR-BI）是培养的小鼠肾上腺皮质细胞中高密度脂蛋白胆固醇进入类固醇生成途径的主要途径。
Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13600-5. doi: 10.1073/pnas.94.25.13600.
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A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism.对编码高密度脂蛋白（HDL）受体I型B类清道夫受体的小鼠基因进行的靶向突变揭示了其在HDL代谢中的关键作用。
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9
The other side of scavenger receptors: pattern recognition for host defense.清道夫受体的另一面：宿主防御的模式识别
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10
Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells.清道夫受体B1（SR-B1）底物可抑制大鼠肝实质细胞对高密度脂蛋白胆固醇酯的选择性摄取。
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