Christopherson W M, Lundin F E, Mendez W M, Parker J E
Cancer. 1976 Sep;38(3):1357-66. doi: 10.1002/1097-0142(197609)38:3<1357::aid-cncr2820380340>3.0.co;2-a.
Data from a 21-year period are presented to evaluate the effects of a mass cytologic screening program on uterine cancer morbidity and mortality in Louisville, Jefferson County, Kentucky. The success of screening was greatest in the younger age groups. There was a fall-off after age 45 years, especially in those age 60 years or older. Women at highest risk for cervical cancer, in the low socioeconomic quartile, had a better initial screening rate than the two middle-income quartiles, and had the highest rate of all women for subsequent rescreening. The greatest decrease in both morbidity and mortality was in women under the age of 50 years. Women age 30-39 and 50-59 years benefitted the most, as measured by mortality, with a decrease of 70.8 and 69.0%, respectively. There was no change in mortality rates for those age 70 years or older. Although the average annual age-adjusted rate increased from 13.2 to 15.3/100,000 women over the 21-year period.
本文呈现了21年间的数据,以评估大规模细胞学筛查项目对肯塔基州杰斐逊县路易斯维尔市子宫癌发病率和死亡率的影响。筛查的成功率在较年轻年龄组中最高。45岁以后出现下降,尤其是60岁及以上人群。社会经济地位最低四分位数中患宫颈癌风险最高的女性,其初始筛查率高于两个中等收入四分位数的女性,且在所有女性中后续重新筛查率最高。发病率和死亡率下降幅度最大的是50岁以下女性。以死亡率衡量,30 - 39岁和50 - 59岁的女性受益最大,分别下降了70.8%和69.0%。70岁及以上人群的死亡率没有变化。尽管在这21年期间,年龄调整后的年均发病率从每10万名女性13.2例增至15.3例。