Hinds M W, Skaggs J W, Allen D T
South Med J. 1984 Apr;77(4):431-5. doi: 10.1097/00007611-198404000-00006.
We compared the average annual age-adjusted, sex- and site-specific cancer mortality rates among Kentuckians during two five-year time periods: 1971 to 1975 and 1976 to 1980. Lung cancer alone showed a statistically significant increase in mortality rates for both sexes, but significant increases were also found for skin cancer and leukemias among men and for pancreatic cancer and lymphomas among women. Significant decreases in mortality rates were observed for cancer of the rectum and stomach in both sexes, lymphomas among men, and leukemias and liver and uterine (corpus and cervix) cancer among women. Increased lung cancer mortality rates occurred for all age groups of women aged 35 and over, but in men, decreased lung cancer mortality rates were observed for ages 35 to 49 and increased rates only after age 50. All age groups of women experienced substantial declines in cervical cancer mortality rates. Without the dramatic increase in lung cancer mortality during this period, overall cancer mortality rates would have shown almost no change among Kentucky men and would have decreased among Kentucky women.
我们比较了肯塔基州人在两个五年时间段(1971年至1975年和1976年至1980年)中按年龄、性别和部位调整后的年均癌症死亡率。仅肺癌在两性中的死亡率均有统计学显著升高,但男性的皮肤癌和白血病以及女性的胰腺癌和淋巴瘤的死亡率也有显著升高。两性的直肠癌和胃癌、男性的淋巴瘤以及女性的白血病、肝癌和子宫癌(子宫体和子宫颈)的死亡率均显著下降。35岁及以上各年龄组女性的肺癌死亡率均有所上升,但男性中,35至49岁的肺癌死亡率下降,50岁以后才上升。各年龄组女性的宫颈癌死亡率均大幅下降。若在此期间肺癌死亡率没有急剧上升,肯塔基州男性的总体癌症死亡率几乎不会有变化,而肯塔基州女性的总体癌症死亡率则会下降。