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[对化疗有反应的恶性非霍奇金淋巴瘤的心肌定位]

[Myocardial localization of malignant non-Hodgkin lymphoma responsive to chemotherapy].

作者信息

Cracowski J L, Trémel F, Nicolini F, Bost F, Mallion J M

机构信息

Service de médecine interne et cardiologie, CHU Grenoble.

出版信息

Arch Mal Coeur Vaiss. 1997 Nov;90(11):1527-31.

PMID:9539827
Abstract

Cardiac malignant non-hodgkinian lymphoma, which is usually asymptomatic, is observed in 15 to 25% of autopsy cases of this condition. The authors report an unusual case of myocardial lymphoma diagnosed during pulmonary oedema. Echocardiography showed left ventricular hypertrophy with increased echogenicity of the myocardial walls and marked decrease in left ventricular ejection fraction. Myocardial biopsy confirmed the diagnosis of a high grade malignant lymphoma. The disease responded to chemotherapy. Early diagnosis of myocardial involvement of a lymphoma, presenting with non-specific electrocardiographic changes, requires investigation by histological study of a myocardial biopsy. This invasive technique is justified because of its therapeutic implications.

摘要

心脏恶性非霍奇金淋巴瘤通常无症状,在该疾病的尸检病例中占15%至25%。作者报告了一例在肺水肿期间诊断出的心肌淋巴瘤罕见病例。超声心动图显示左心室肥厚,心肌壁回声增强,左心室射血分数显著降低。心肌活检证实为高级别恶性淋巴瘤。该疾病对化疗有反应。对于表现为非特异性心电图改变的淋巴瘤心肌受累的早期诊断,需要通过心肌活检的组织学研究进行调查。由于其治疗意义,这种侵入性技术是合理的。

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