Brembilla-Perrot B, Jacquemin L, Beurrier D, Houplon P, Terrier de la Chaise A, Louis P, Bailly L, Berder V, Danchin N
Service de cardiologie A, CHU de Brabois, Vandoeuvre-les-Nancy.
Arch Mal Coeur Vaiss. 1997 Oct;90(10):1363-8.
Programmed atrial stimulation is a technique increasingly used to assess different pathologies but the reproducibility of the results is totally unknown. The aim of this study was to determine its reproducibility. Two electrophysiological studies were undertaken without antiarrhythmic therapy in an interval of one to three months (average 18 months) in 48 patients. The programmed atrial stimulation used 1 and 2 extrastimuli delivered in sinus rhythm and then three paced rhythms (sinus cycle -10%, 600 ms, 400 ms). Twenty-one patients had documented atrial arrhythmias (atrial fibrillation n = 13, flutter n = 3 or tachycardia n = 5) (group 1) and the 27 other patients had no spontaneous arrhythmias (group II). In group I, clinical tachycardial was reproduced in 18 patients during the initial stimulation procedure. During the second investigation, 17 remained inducible and in the 3 in whom stimulation was negative, it remained so in 2 of the cases. The reproducibility was therefore 90%. In group II, 12 patients had inducible sustained (for over 1 minute) tachycardia during the first procedure (44%) but this only remained inducible in 6 patients. In the other 15 subjects, stimulation was negative during the first procedure but 7 of them had inducible tachycardial during the second procedure. The reproducibility of the technique was therefore only of 52%. The authors conclude that the reproducibility of programmed atrial stimulation in patients with documented spontaneous paroxysmal arrhythmias is excellent. However, the reproducibility is mediocre in subjects without spontaneous arrhythmias and the induction of tachycardial in this group of patients should be interpreted with caution given the variability of the response to programmed atrial stimulation.
程控心房刺激是一种越来越多地用于评估不同病理状况的技术,但结果的可重复性完全未知。本研究的目的是确定其可重复性。在48例患者中,在1至3个月(平均18个月)的间隔内进行了两次无抗心律失常治疗的电生理研究。程控心房刺激采用在窦性心律下发放1个和2个额外刺激,然后采用三种起搏心律(窦性周期-10%、600毫秒、400毫秒)。21例患者有记录的房性心律失常(心房颤动n = 13、心房扑动n = 3或心动过速n = 5)(第1组),另外27例患者无自发心律失常(第II组)。在第1组中,18例患者在初始刺激过程中再现了临床心动过速。在第二次检查时,17例仍可诱发,在3例刺激为阴性的患者中,2例仍为阴性。因此,可重复性为90%。在第II组中,12例患者在第一次检查时有可诱发的持续性(超过1分钟)心动过速(44%),但只有6例仍可诱发。在其他15例受试者中,第一次检查时刺激为阴性,但其中7例在第二次检查时有可诱发的心动过速。因此,该技术的可重复性仅为52%。作者得出结论,在有记录的自发性阵发性心律失常患者中,程控心房刺激的可重复性极佳。然而,在无自发心律失常的受试者中,可重复性一般,鉴于对程控心房刺激反应的变异性,对这组患者心动过速的诱发应谨慎解释。