Scondotto G, Catena G, Aloisi D
Servizio di Angiologia, Azienda USL, Città di Bologna.
Minerva Med. 1997 Dec;88(12):537-41.
Twenty-five female patients suffering from primary venous insufficiency of the lower limbs underwent parenteral and oral treatment with mesoglycan for 3 months. In addition to an evaluation of the subjective and objective parameters linked to venous insufficiency, all patients underwent lower limb venous echo colour-Doppler and videocapillaroscopy using an optic probe in a perimalleolar or periulcerous site. At the end of treatment, all patients reported an improvement in subjective parameters, which was confirmed by a reduction of distal edema in 22 out of 25 cases. There was also an improvement in capillaroscopic findings (reduction of edema of pericapillary connective tissue, reduction of capillary and venular ectasia.
25名患有原发性下肢静脉功能不全的女性患者接受了3个月的葡糖胺聚糖肠外和口服治疗。除了评估与静脉功能不全相关的主观和客观参数外，所有患者均在踝关节周围或溃疡周围部位使用光学探头进行了下肢静脉彩色多普勒超声检查和视频毛细血管镜检查。治疗结束时，所有患者均报告主观参数有所改善，25例中有22例远端水肿减轻证实了这一点。毛细血管镜检查结果也有所改善（毛细血管周围结缔组织水肿减轻、毛细血管和小静脉扩张减轻）。
