[记忆的神经免疫机制的系统分析]
[Systemic analysis of neuroimmune mechanisms of memory].
作者信息
Zhuravlev B V, Murtazina E P, Sulin V Iu
机构信息
P. K. Anokhin Institute of Normal Physiology, Russian Acad. Med. Sci., Moscow, Russia.
出版信息
Ross Fiziol Zh Im I M Sechenova. 1997 Nov-Dec;83(11-12):19-28.
PMID:9541953
Abstract
Administration of IL-1 beta and 125-129 fragment of alpha 2-interferon improved learning and retention of active avoidance behaviour in memory in rats. It also improved the correlation between intersignal runs and success of the avoidance behaviour learning. The data obtained suggest that an activation of the intersignal retention process is one of the mechanisms of the immunomodulators effect on learning and memory.
摘要
给予白细胞介素-1β和α2-干扰素的125-129片段可改善大鼠记忆中主动回避行为的学习和保持。它还改善了信号间期奔跑与回避行为学习成功率之间的相关性。所获得的数据表明，信号间期保持过程的激活是免疫调节剂对学习和记忆产生影响的机制之一。
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