Saif M W, Morse E E, Greenberg B R
University of Connecticut School of Medicine, USA.
Conn Med. 1998 Feb;62(2):67-70.
Though positive direct antiglobulin tests are common in AIDS patients, overt hemolysis is rare. A hypercoagulable state has recently been recognized in these patients and may contribute to the thromboembotic complications previously reported in three patients with HIV-associated autoimmune hemolytic anemia.
An AIDS patient with severe warm autoimmune hemolytic anemia developed a pulmonary embolus after a single red blood cell transfusion.
There may be an increased risk of thromboembolism in AIDS patients with autoimmune hemolytic anemia who receive red blood cell transfusions, a concern we have previously raised. Prophylactic anticoagulation should be considered in this setting.
尽管艾滋病患者中直接抗球蛋白试验阳性很常见，但明显的溶血却很少见。最近在这些患者中认识到一种高凝状态，这可能是先前报道的3例HIV相关自身免疫性溶血性贫血患者发生血栓栓塞并发症的原因。
一名患有严重温抗体型自身免疫性溶血性贫血的艾滋病患者在接受一次红细胞输血后发生了肺栓塞。
接受红细胞输血的艾滋病自身免疫性溶血性贫血患者发生血栓栓塞的风险可能增加，这是我们之前提出的一个问题。在这种情况下应考虑预防性抗凝。
