胃浆母细胞淋巴瘤。病例报告。
Plasmablastic lymphoma of the stomach. A case report.
作者信息
Pruneri G, Graziadei G, Ermellino L, Baldini L, Neri A, Buffa R
机构信息
II Servizio di Anatomia Patologica, Istituto di Scienze Mediche, IRCCS Ospedale Maggiore di Milan, Italy.
出版信息
Haematologica. 1998 Jan;83(1):87-9.
We report the case of a 53 year-old woman with a gastric tumor showing morphological, phenotypical and molecular features of a plasmablastic lymphoma, a recently recognized subtype of diffuse large B-cell lymphoma. The tumor was composed of plasmablast-like cells, lacked CD45 and B-cell associated antigens, expressed the plasma cell-associated antigen CD38, and showed clonally rearranged IgH genes in the absence of bcl-2 and bcl-6 genes rearrangement.
我们报告了一例53岁女性胃肿瘤病例，该肿瘤呈现出浆母细胞性淋巴瘤的形态、表型和分子特征，浆母细胞性淋巴瘤是弥漫性大B细胞淋巴瘤最近被认可的一个亚型。肿瘤由浆母细胞样细胞组成，缺乏CD45和B细胞相关抗原，表达浆细胞相关抗原CD38，并且在不存在bcl-2和bcl-6基因重排的情况下显示出克隆性重排的IgH基因。
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