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[发热或体温过低的家兔血液中甲胎蛋白和性类固醇激素含量的变化]

[Change in the content of alpha-fetoprotein and sex steroid hormones in the blood of rabbits in fever or subnormal temperature].

作者信息

Semenenia I N

出版信息

Patol Fiziol Eksp Ter. 1998 Jan-Mar(1):26-8.

PMID:9542402
Abstract

In experiments on rabbits, changes in the content of alpha-fetoprotein, estradiol and progesterone in blood serum in fever and subnormal temperature simulated with the use of pyrogenal and Freund's complete adjuvant were studied. The concentration of alpha-fetoprotein decreased and that of estradiol and progesterone increased. The results were analyzed in terms of the return of certain signs and properties in disease to the period of antenatal ontogenesis. A possible relation between the changes in alpha-fetoprotein in fever, subnormal temperature and immune, hormonal mechanisms of the thermoregulatory disorder was hypothesized.

摘要

在对兔子的实验中,研究了使用热原和弗氏完全佐剂模拟发热和体温过低时血清中甲胎蛋白、雌二醇和孕酮含量的变化。甲胎蛋白浓度降低,雌二醇和孕酮浓度升高。根据疾病中某些体征和特性恢复到产前发育阶段的情况对结果进行了分析。推测了发热、体温过低时甲胎蛋白变化与体温调节紊乱的免疫、激素机制之间可能存在的关系。

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