Tennstedt C, Chaoui R, Bollmann R, Dietel M
Department of Pathology, Charité Hospital, Humboldt University, Berlin, Germany.
Pathol Res Pract. 1998;194(1):55-8. doi: 10.1016/S0344-0338(98)80012-5.
We report the prenatal diagnosis of an angiomyxoma of the umbilical cord in a female fetus of a dizygotic twin pregnancy. The pregnant woman was hospitalized at 18 weeks for exclusion of a suspected exomphalos. Using high-resolution ultrasound and color doppler, the umbilical tumor (8 x 5 x 4 cm) was suspected to be an angiomyxoma without malformations in the fetus. Neither chromosomal aberrations nor elevated alphafetoprotein were found after amniocentesis. Serial examinations showed an increase in the size of the cystic mass without deterioration of the fetal condition. Macroscopical and microscopical examinations of the tumor performed after delivery revealed an angiomyxoma with cystic degeneration of Wharton's jelly. Tumors of the umbilical cord are rare anomalies and should be considered when using prenatal ultrasound for detection of cystic lesions.
我们报告了一例双卵双胎妊娠女性胎儿脐带血管黏液瘤的产前诊断。该孕妇在孕18周时因排除疑似脐膨出而住院。使用高分辨率超声和彩色多普勒检查，怀疑脐带肿瘤（8×5×4cm）为血管黏液瘤，胎儿无畸形。羊膜腔穿刺术后未发现染色体异常及甲胎蛋白升高。系列检查显示囊性肿物大小增加，但胎儿状况未恶化。分娩后对肿瘤进行的大体和显微镜检查显示为血管黏液瘤，伴有华通胶的囊性变。脐带肿瘤是罕见的异常情况，在产前超声检测囊性病变时应予以考虑。
