Woods R K, Abramson M, Raven J M, Bailey M, Weiner J M, Walters E H
Dept of Respiratory Medicine, Monash Medical School and Alfred Hospital, Melbourne, Australia.
Eur Respir J. 1998 Jan;11(1):151-5. doi: 10.1183/09031936.98.11010151.
The aim of the study was to assess the ability of the European Community Respiratory Health Survey (ECRHS) questionnaire to provide data on the prevalence, type and reported symptoms associated with food intolerance from a group of young adults in Melbourne. Six hundred and sixty nine randomly selected subjects completed the questionnaire with 553 attending the laboratory for skin-prick tests, anthropometry, and ventilatory function tests. A further 207 symptomatic participants completed the questionnaire, with 204 of them attending the laboratory. Seventeen per cent of all respondents reported food intolerance or food allergy. A wide variety of food items was cited as being responsible for food-related illnesses. Those with current asthma did not report food-related illness more frequently than those without asthma. Respondents who reported respiratory symptoms following food ingestion were more likely to be atopic, to have used inhaled respiratory medications in the previous 12 months, reported less exposure to regular passive smoking over the past 12 months and weighed more. These associations between respiratory symptoms and food intolerance require further prospective investigation and verification. The importance of using appropriate dietary methodology in future studies for determining diet-disease relationships was highlighted by this study.
该研究的目的是评估欧洲共同体呼吸健康调查(ECRHS)问卷能否提供有关墨尔本一组年轻人食物不耐受的患病率、类型及报告症状的数据。669名随机挑选的受试者完成了问卷,其中553人前往实验室进行皮肤点刺试验、人体测量和通气功能测试。另有207名有症状的参与者完成了问卷,其中204人前往实验室。所有受访者中有17%报告有食物不耐受或食物过敏。多种食物被认为是导致与食物相关疾病的原因。目前患有哮喘的人报告与食物相关疾病的频率并不比没有哮喘的人更高。在摄入食物后报告有呼吸道症状的受访者更有可能是特应性体质,在过去12个月内使用过吸入性呼吸药物,在过去12个月内报告较少接触经常性被动吸烟,且体重更重。呼吸道症状与食物不耐受之间的这些关联需要进一步的前瞻性调查和验证。本研究强调了在未来研究中使用适当饮食方法来确定饮食与疾病关系的重要性。