Wada M, Baba H, Imura S, Morita A, Kusaka Y
Department of Orthopaedic Surgery, School of Medicine, Fukui Medical University, Japan.
Clin Exp Rheumatol. 1998 Jan-Feb;16(1):15-20.
To examine the relationship between radiographic abnormalities and arthroscopic findings of the cartilage lesions in patients with osteoarthritis (OA) of the knee.
Arthroscopy was performed in 190 patients with primary medial compartment (MC) OA of the knee to assess the severity of the cartilage lesion. Standing radiographs of all patients were graded according to the joint space narrowing (JSN) and Kellgren-Lawrence (K/L) scales. In addition to evaluating the correlation between arthroscopic articular cartilage lesions and the radiographic scale, multiple regression analysis was used to identify the arthroscopic findings and clinical factors that influenced the cartilage lesions.
The positive predictive values of the JSN and K/L scales of the MC for the presence of essentially abnormal articular cartilage in the MC by arthroscopy were high (0.98, 0.96, respectively). The sensitivity and specificity of the JSN scale and the sensitivity and negative predictive value of the K/L scale were also high in the MC. In contrast, the positive predictive values of these radiographic scales for the presence of arthroscopic lesions in the lateral compartment (LC) were poor (0.20 and 0.19). In this study population with severe OA, there were more patients with a high K/L score than with a high JSN score in the MC.
In MC-OA of the knee, the JSN and K/L scores for the MC correlated highly with cartilage lesions of the MC by arthroscopy. However, the cartilage lesion of the LC correlated poorly with both of these radiographic scales.
探讨膝关节骨关节炎(OA)患者软骨损伤的影像学异常与关节镜检查结果之间的关系。
对190例原发性膝关节内侧间室(MC)OA患者进行关节镜检查,以评估软骨损伤的严重程度。根据关节间隙狭窄(JSN)和Kellgren-Lawrence(K/L)量表对所有患者的站立位X线片进行分级。除了评估关节镜下关节软骨损伤与影像学量表之间的相关性外,还采用多元回归分析来确定影响软骨损伤的关节镜检查结果和临床因素。
MC的JSN和K/L量表对关节镜检查发现MC存在基本异常关节软骨的阳性预测值较高(分别为0.98、0.96)。JSN量表的敏感性和特异性以及K/L量表的敏感性和阴性预测值在MC中也较高。相比之下,这些影像学量表对外侧间室(LC)存在关节镜损伤的阳性预测值较差(分别为0.20和0.19)。在这个重度OA研究人群中,MC中K/L评分高的患者比JSN评分高的患者更多。
在膝关节MC-OA中,MC的JSN和K/L评分与关节镜检查发现的MC软骨损伤高度相关。然而,LC的软骨损伤与这两种影像学量表的相关性均较差。