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水痘期间与冷凝集素相关的溶血性贫血及文献综述

Hemolytic anemia associated with cold agglutinin during chickenpox and a review of the literature.

作者信息

Terada K, Tanaka H, Mori R, Kataoka N, Uchikawa M

机构信息

Department of Pediatrics, Kawasaki Medical School, Okayama, Japan.

出版信息

J Pediatr Hematol Oncol. 1998 Mar-Apr;20(2):149-51. doi: 10.1097/00043426-199803000-00012.

DOI:10.1097/00043426-199803000-00012
PMID:9544167
Abstract

PURPOSE

To describe the findings and cause of anemia and jaundice in a 2-year-old boy.

PATIENT AND METHODS

This boy was admitted with a hemoglobin of 7.8 g/dL, a bilirubin of 1.8 mg/dL, and increased urobilinogen.

RESULTS

On the second day after admission, hemolytic anemia associated with an anti-I cold agglutinin was diagnosed, which was transient and recovered without any treatment.

CONCLUSION

This is a very rare complication of chickenpox; only five cases have been previously reported and these were all characterized by anti-Pr cold agglutinin with hemolytic anemia after the onset of chickenpox. We report the first case of hemolytic anemia associated with an anti-I cold agglutinin during the incubation period of chickenpox.

摘要

目的

描述一名2岁男孩贫血和黄疸的检查结果及病因。

患者与方法

该男孩入院时血红蛋白为7.8 g/dL,胆红素为1.8 mg/dL,尿胆原增加。

结果

入院后第二天,诊断为与抗I型冷凝集素相关的溶血性贫血,该病为一过性,未经任何治疗即康复。

结论

这是水痘非常罕见的并发症;此前仅报道过5例,均表现为水痘发病后出现与抗Pr型冷凝集素相关的溶血性贫血。我们报告了首例水痘潜伏期与抗I型冷凝集素相关的溶血性贫血病例。

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Hemolytic anemia associated with cold agglutinin during chickenpox and a review of the literature.水痘期间与冷凝集素相关的溶血性贫血及文献综述
J Pediatr Hematol Oncol. 1998 Mar-Apr;20(2):149-51. doi: 10.1097/00043426-199803000-00012.
2
Cold agglutinin disease after chicken pox. An uncommon complication of a common disease.水痘后冷凝集素病。一种常见疾病的罕见并发症。
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[Cold agglutinin hemolytic anemia complicating mycoplasma pneumonia].[支原体肺炎并发冷凝集素溶血性贫血]
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Autoimmune Hemolytic Anemia due to Varicella Infection.水痘感染所致自身免疫性溶血性贫血
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Development of mixed-type autoimmune hemolytic anemia and Evans' syndrome following chicken pox infection in a case of low-titer cold agglutinin disease.一例低滴度冷凝集素病患者水痘感染后发生混合型自身免疫性溶血性贫血和伊文氏综合征
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