Ray J F, Lawton B R, Magnin G E, Dovenbarger W V, Smullen W A, Reyes C N, Myers W O, Wenzel F J, Sautter R D
Chest. 1976 Sep;70(03):332-6. doi: 10.1378/chest.70.3.332.
We reviewed 179 patients who had undergone thoracotomy and resection of a suspected malignant coin lesion of the lung over the past 20 years to see if a policy of early thoracotomy was therapeutically valid. The average diameter of all lesions was 1.6 cm; the average diameter of 27 malignant lesions (15 percent) was 1.8 cm. Follow-up of the 27 patients with malignant neoplasms was 100 percent. The present survival rate of the 19 patients with primary lung cancer is 89 percent (17/19). Of 12 cases of primary lung cancer followed for five years, ten (83 percent) survived. The five-year survival of the eight patients with metastatic lesions was 25 percent (2/8). There were no postoperative deaths and few serious postoperative complications (four patients or 2 percent). Very small primary lung cancers detected and treated early do have the same poor prognosis as larger primary cancers.
我们回顾了过去20年中179例接受开胸手术并切除疑似肺部恶性硬币状病变的患者,以探讨早期开胸手术策略在治疗上是否有效。所有病变的平均直径为1.6厘米;27个恶性病变(15%)的平均直径为1.8厘米。对27例恶性肿瘤患者的随访率为100%。19例原发性肺癌患者目前的生存率为89%(17/19)。在12例随访5年的原发性肺癌病例中,10例(83%)存活。8例转移性病变患者的5年生存率为25%(2/8)。无术后死亡病例,术后严重并发症极少(4例患者,占2%)。早期发现并治疗的极小原发性肺癌与较大原发性肺癌的预后同样较差。