Simon G E, Revicki D A, Grothaus L, Vonkorff M
Center for Health Studies, Group Health Cooperative, Seattle, WA 98101-1448, USA.
Med Care. 1998 Apr;36(4):567-72. doi: 10.1097/00005650-199804000-00012.
Data from 536 primary care patients initiating antidepressant treatment were used to examine the performance of the Medical Outcomes Study SF-36 Physical Component and Mental Component summary scores.
The SF-36 was administered at baseline and readministered after 1 month and 3 months (n = 482).
At the baseline assessment, patients reported modest impairment on the Physical Function, Role--Physical, Bodily Pain, and General Health Perceptions subscales (0.10 to 0.68 standard deviations below national norms), but the Physical Component summary (mean = 51) indicated no impairment based on a population norm of 50. During 3 months of follow-up evaluation, the Physical Function, Role--Physical, Bodily Pain, and General Health Perceptions subscales all showed moderate and statistically significant improvement (range from 0.28 to 0.49 standard deviation units), whereas the Physical Component summary score was essentially unchanged (mean = 50 at both 1-month and 3-month assessments). This pattern of results is a natural consequence of the assumptions and methods used to calculate these summary scores-orthogonal factor rotation and negative scoring coefficients.
These findings suggest caution in the interpretation of Mental Component Summary and Physical Component Summary scores when the condition or treatment of interest has strong effects on scales with negative scoring coefficients (Mental Health and Role--Emotional for the Physical Component; Physical Function, Role--Physical, and Bodily Pain for the Mental Component).
使用536例开始抗抑郁治疗的初级保健患者的数据,来检验医学结局研究简明健康调查量表(SF - 36)身体成分和心理成分总结得分的表现。
在基线时进行SF - 36测评,并在1个月和3个月后再次测评(n = 482)。
在基线评估时,患者在身体功能、身体角色功能、身体疼痛和总体健康感知分量表上报告有中度损害(比全国常模低0.10至0.68个标准差),但身体成分总结得分(均值 = 51)基于50的总体常模表明没有损害。在3个月的随访评估中,身体功能、身体角色功能、身体疼痛和总体健康感知分量表均显示出中度且具有统计学意义的改善(范围为0.28至0.49个标准差单位),而身体成分总结得分基本未变(1个月和3个月评估时均值均为50)。这种结果模式是用于计算这些总结得分的假设和方法(正交因子旋转和负计分系数)的自然结果。
这些发现表明,当感兴趣的疾病或治疗对具有负计分系数的量表有强烈影响时(身体成分中的心理健康和情绪角色功能;心理成分中的身体功能、身体角色功能和身体疼痛),在解释心理成分总结得分和身体成分总结得分时要谨慎。