溶液中烟草花叶病毒的60纳米分辨率光学化学成像。
Optical chemical imaging of tobacco mosaic virus in solution at 60-nm resolution.
作者信息
Keller T H, Rayment T, Klenerman D
机构信息
Department of Chemistry, University of Cambridge, England.
出版信息
Biophys J. 1998 Apr;74(4):2076-9. doi: 10.1016/S0006-3495(98)77914-7.
Abstract
Scanning near-field optical microscopy can provide images with a resolution less than the wavelength of light, and therefore ought in principle to be of great value in studies of biological structures. In this work we show how for the first time images have been obtained of tobacco mosaic virus particles at 60-nm resolution, combined with chemical imaging using monoclonal antibodies under in vitro conditions.
摘要
扫描近场光学显微镜能够提供分辨率小于光波长的图像，因此原则上在生物结构研究中应具有巨大价值。在这项工作中，我们展示了首次在体外条件下，以60纳米分辨率获得烟草花叶病毒颗粒的图像，并结合使用单克隆抗体进行化学成像。
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