McGuire G, Wright F
Biomathematics and Statistics Scotland, King's Buildings, Edinburgh, UK.
Bioinformatics. 1998;14(2):219-20. doi: 10.1093/bioinformatics/14.2.219.
TOPAL scans a multiple sequence alignment for evidence of recombinant sequences, prior to phylogenetic analysis.
The TOPAL package may be accessed at http://www.bioss.sari.ac.uk/grainne, and by anonymous ftp at ftp.bioss. sari.ac.uk in the directory pub/phylogeny/topal.
在进行系统发育分析之前,TOPAL会扫描多序列比对以寻找重组序列的证据。