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[一名成年女性和一名老年女性的咽后脓肿]

[Retropharyngeal abscess in an adult and an elderly woman].

作者信息

Miyazaki T, Ito Y, Kato M, Akita S, Mizuta K, Miyata H, Kato N, Watanabe K

机构信息

Department of Otorhinolaryngology, Gifu University School of Medicine.

出版信息

Kansenshogaku Zasshi. 1998 Feb;72(2):157-61. doi: 10.11150/kansenshogakuzasshi1970.72.157.

Abstract

Retropharyngeal abscess is reported to be decreasing in frequency in recent years. We report two cases of retropharyngeal abscess that were diagnosed within four years in Department of Otorhinolaryngology, Gifu University Hospital. Case 1 was a 36-year-old male who was suggested to have an abscess as primary infection and case 2 was a 71-year-old female whose abscess seemed to be a secondary infection following unknown primary infection. Endoscopic or open neck drainage as well as antibacterial chemotherapy mainly with combinations of flomoxef and clindamycin in the case 1 and piperacillin and clindamycin in the case 2 was successfully carried out. They were discharged an 15-day and 24-day after operation in the cases 1 and 2, respectively. A 30 min. culture after sample collection on operation demonstrated aerobe-anaerobe mixed infection in both cases; three aerobes and four anaerobes in the case 1 and three aerobes and two anaerobes in the case 2. These results suggest that retropharyngeal abscess may be a complicated infection involving more bacterial species than has been commonly believed. Measuring susceptibility of isolates to antimicrobial agents, a strain of Capnocytophaga sp. and a strain of anaerobic gram-negative rod were highly resistant to piperacillin, cefroxine and ofloxacin. It is important for adequate antibacterial chemotherapy to grasp the bacteriology of retropharyngeal abscess and analyze susceptibility of antimicrobial agents.

摘要

据报道,近年来咽后脓肿的发病率呈下降趋势。我们报告了岐阜大学医院耳鼻喉科在四年内诊断出的两例咽后脓肿病例。病例1是一名36岁男性,被诊断为原发性感染引起的脓肿;病例2是一名71岁女性,其脓肿似乎是在不明原发性感染后继发的感染。分别对病例1主要采用氟氧头孢和克林霉素联合、病例2采用哌拉西林和克林霉素联合进行内镜或开放性颈部引流以及抗菌化疗,均取得成功。病例1和病例2分别在术后15天和24天出院。手术时采集样本后进行的30分钟培养显示,两例均为需氧菌-厌氧菌混合感染;病例1有3种需氧菌和4种厌氧菌,病例2有3种需氧菌和2种厌氧菌。这些结果表明,咽后脓肿可能是一种比通常认为的涉及更多细菌种类的复杂感染。通过检测分离菌株对抗菌药物的敏感性发现,一株二氧化碳嗜纤维菌和一株厌氧革兰氏阴性杆菌对哌拉西林、头孢氨苄和氧氟沙星高度耐药。掌握咽后脓肿的细菌学情况并分析抗菌药物的敏感性对于进行充分的抗菌化疗很重要。

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