Kager P A
Afd. Inwendige Geneeskunde, onderafd. Infectieziekten, Tropische Geneeskunde en Aids, Universiteit van Amsterdam/Academisch Medisch Centrum.
Ned Tijdschr Geneeskd. 1997 Sep 13;141(37):1764-6.
The natural products quinine and artemisinine have been effective antimalarials for centuries. Most synthetic antimalarials were developed because of pressure of war; against all some degree of resistance has developed. The newer drugs are too expensive for large-scale use. Development of new antimalarials is financially too risky for the pharmaceutical industry. Co-operation among industries, research institutes, governments and international organizations is coming off the ground. Dutch researchers should contribute to international malaria research for humanitarian reasons and out of self-interest, for the benefit of public health.
几个世纪以来,天然产物奎宁和青蒿素一直是有效的抗疟药物。大多数合成抗疟药物是在战争压力下研发出来的;尽管如此,某种程度的抗药性还是出现了。这些新药价格太贵,无法大规模使用。对制药行业来说,研发新的抗疟药物在经济上风险太大。各行业、研究机构、政府和国际组织之间的合作正在起步。出于人道主义原因和自身利益,荷兰研究人员应该为国际疟疾研究做出贡献,以造福公众健康。