通过细胞遗传学和荧光原位杂交技术对恶性小汗腺汗孔瘤进行特征分析。
Characterization of a malignant eccrine poroma by cytogenetic and fluorescence in situ hybridization techniques.
作者信息
Jin Y, Jin C, Mertens F, Persson B, Jonsson N
机构信息
Department of Clinical Genetics, University Hospital, Lund, Sweden.
出版信息
Cancer Genet Cytogenet. 1998 Apr 15;102(2):100-3. doi: 10.1016/s0165-4608(97)00347-6.
We have cytogenetically and by fluorescence in situ hybridization (FISH) analyzed short-term cultures from a malignant eccrine poroma, a type of tumor in which chromosomal abnormalities have previously not been reported. Combining the results from G-banding and FISH, the karyotype was interpreted as 50,XX,t(3;11;12)(q21;p15;q15),+5,+7,+9, +9,t(12;22)(q13;q13),+del(12)(q15),der(15)t(3;15) (q23;p13),der(17)t(8;17)(q22;p13),-20,add(22)(q13).
我们通过细胞遗传学和荧光原位杂交（FISH）技术分析了恶性小汗腺汗孔瘤的短期培养物，此前尚未有关于该肿瘤染色体异常的报道。结合G显带和FISH的结果，核型被解释为50,XX,t(3;11;12)(q21;p15;q15),+5,+7,+9, +9,t(12;22)(q13;q13),+del(12)(q15),der(15)t(3;15) (q23;p13),der(17)t(8;17)(q22;p13),-20,add(22)(q13) 。
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