Cappell M S
Department of Medicine, Maimonides Medical Center, Brooklyn, New York, USA.
Gastroenterol Clin North Am. 1998 Mar;27(1):37-71. doi: 10.1016/s0889-8553(05)70347-2.
More than 12,000 pregnant patients in the United States per year have conditions normally evaluated by esophagogastroduodenoscopy (EGD). More than 6000 pregnant patient in the United States per year have conditions normally evaluated by sigmoidoscopy or colonoscopy. Endoscopy during pregnancy raises the unique issue of fetal safety, and endoscopic medications comprise a significant component of fetal risks from endoscopy. This article analyzes the safety of endoscopic medications during pregnancy, reviews the literature on the safety of gastrointestinal endoscopy during pregnancy, proposes guidelines for endoscopic indications during pregnancy, and describes modifications of gastrointestinal endoscopy during pregnancy to increase fetal and maternal safety.
美国每年有超过12000名孕妇患有通常需通过食管胃十二指肠镜检查（EGD）来评估的疾病。美国每年有超过6000名孕妇患有通常需通过乙状结肠镜检查或结肠镜检查来评估的疾病。孕期进行内镜检查引发了胎儿安全这一独特问题，而内镜用药是内镜检查给胎儿带来风险的重要组成部分。本文分析了孕期内镜用药的安全性，回顾了关于孕期胃肠内镜检查安全性的文献，提出了孕期内镜检查适应证的指南，并描述了孕期胃肠内镜检查的改进措施以提高胎儿和母亲的安全性。
