Singer B R, McLauchlan G J, Robinson C M, Christie J
Edinburgh Orthopaedic Trauma Unit, Royal Infirmary of Edinburgh, Scotland, UK.
J Bone Joint Surg Br. 1998 Mar;80(2):243-8. doi: 10.1302/0301-620x.80b2.7762.
We report a prospective study of the incidence of fractures in the adult population of Edinburgh, related to age and gender. Over a two-year period, 15,293 adults, 7428 males and 7865 females, sustained a fracture, and 5208 (34.0%) required admission. Between 15 and 49 years of age, males were 2.9 times more likely to sustain a fracture than females (95% CI 2.7 to 3.1). Over the age of 60 years, females were 2.3 times more likely to sustain a fracture than males (95% CI 2.1 to 2.4). There were three main peaks of fracture distribution: the first was in young adult males, the second was in elderly patients of both genders, mainly in metaphyseal bone such as the proximal femur, although diaphyseal fractures also showed an increase in incidence. The third increase in the incidence of fractures, especially of the wrist, was seen to start at 40 years of age in women. Our study has also shown that 'osteoporotic' fractures became evident in women earlier than expected, and that they were not entirely a postmenopausal phenomenon.
我们报告了一项关于爱丁堡成年人群骨折发生率与年龄和性别的前瞻性研究。在两年时间里，15293名成年人（7428名男性和7865名女性）发生了骨折，其中5208人（34.0%）需要住院治疗。在15至49岁之间，男性发生骨折的可能性是女性的2.9倍（95%置信区间为2.7至3.1）。60岁以上，女性发生骨折的可能性是男性的2.3倍（95%置信区间为2.1至2.4）。骨折分布有三个主要高峰：第一个高峰出现在年轻成年男性中，第二个高峰出现在老年男女患者中，主要发生在干骺端骨，如股骨近端，尽管骨干骨折的发生率也有所增加。骨折发生率的第三次上升，尤其是手腕骨折，在女性40岁时开始出现。我们的研究还表明，“骨质疏松性”骨折在女性中比预期更早出现，而且它们并不完全是绝经后的现象。
