感染猿猴泡沫病毒的人类群体的鉴定。

Identification of a human population infected with simian foamy viruses.

作者信息

Heneine W, Switzer W M, Sandstrom P, Brown J, Vedapuri S, Schable C A, Khan A S, Lerche N W, Schweizer M, Neumann-Haefelin D, Chapman L E, Folks T M

机构信息

HIV and Retrovirology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

Nat Med. 1998 Apr;4(4):403-7. doi: 10.1038/nm0498-403.

DOI:10.1038/nm0498-403

PMID:9546784

Abstract

Studying the transmission of simian retroviruses to humans can help define the importance of these infections to public health. We identified a substantial prevalence (4/231, 1.8%) of infection with simian foamy viruses (SFV) among humans occupationally exposed to nonhuman primates. Evidence of SFV infection included seropositivity, proviral DNA detection and isolation of foamy virus. The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections.

摘要

研究猿猴逆转录病毒向人类的传播有助于明确这些感染对公共卫生的重要性。我们在职业性接触非人灵长类动物的人群中发现猿猴泡沫病毒（SFV）感染率相当高（4/231，1.8%）。SFV感染的证据包括血清阳性、前病毒DNA检测以及泡沫病毒的分离。感染源SFV来自一只非洲绿猴（一人）和狒狒（三人）。这些感染尚未导致疾病或性传播，可能代表良性终末感染。