Martínez de Tejada B, Coll O, de Flores M, Hillier S L, Landers D V
Departamentos de Obstetricia y Ginecología, Magee-Womens Research Institute, University of Pittsburgh, Pensilvania, USA. tejada+@pitt.edu
Med Clin (Barc). 1998 Feb 21;110(6):201-4.
To investigate the prevalence and risk factors of bacterial vaginosis (BV) in a pregnant population of Barcelona (Spain).
301 pregnant women controlled in the Hospital Clinic i Provincial (HCP) of Barcelona were enrolled in the study. Complete epidemiological information, and vaginal samples were available in 293 women. BV was diagnosed by Gram stain of vaginal smear (Nugent's criteria).
BV was detected in 22 pregnant women (7.5%; 95% CI: 4.6-10.5%). There was no association between race, parity, education, marital status, smoking and drug use, and the presence of BV. Non-use of birth control method (72.3% vs 34.4%; p < 0.0001), presence of sexually transmitted diseases (STD) during pregnancy (22.7% vs 3.7%; p < 0.0001), HIV seropositivity (13.6% vs 2.9%; p = 0.041) and presence of symptoms of vaginitis (40.9% vs 13.3%; p = 0.009) were significantly associated with the presence of BV.
The prevalence of BV in a pregnant population of Barcelona (Spain) is 7.5%. Further work is needed to evaluate the usefulness of BV as a prescreening marker for STD and HIV infection. The Gram stain provides an inexpensive, fast and easy method to diagnose BV, and may allow us to screen, treat and prevent the morbidity and mortality associated with it.
调查西班牙巴塞罗那孕妇群体中细菌性阴道病（BV）的患病率及危险因素。
选取在巴塞罗那省立医院诊所（HCP）接受检查的301名孕妇纳入研究。293名孕妇可获取完整的流行病学信息及阴道样本。通过阴道涂片革兰氏染色（努金特标准）诊断BV。
22名孕妇检测出BV（7.5%；95%置信区间：4.6 - 10.5%）。种族、产次、教育程度、婚姻状况、吸烟及药物使用与BV的存在之间无关联。未使用避孕方法（72.3%对34.4%；p < 0.0001）、孕期存在性传播疾病（STD）（22.7%对3.7%；p < 0.0001）、HIV血清学阳性（13.6%对2.9%；p = 0.041）以及存在阴道炎症状（40.9%对13.3%；p = 0.009）与BV的存在显著相关。
西班牙巴塞罗那孕妇群体中BV的患病率为7.5%。需要进一步开展工作以评估BV作为STD和HIV感染预筛查标志物的效用。革兰氏染色提供了一种廉价、快速且简便的BV诊断方法，或许能使我们对与之相关的发病率和死亡率进行筛查、治疗及预防。
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