Darle N, Lim R C
Eur Surg Res. 1976;8(2):132-9. doi: 10.1159/000127854.
Hemorrhage amounting to 40% of the calculated blood volume in dogs produced a fall in systemic blood pressure to a level of approximately 50 mm Hg. This was associated with a decline of total liver blood flow of about 60% of normal. Infusion of low molecular dextran (LMD) or saline of a volume, corresponding to 1/7 of the volume of blood taken out, increased the total liver blood flow. This increase was much more pronounced in the LMD group, maybe due to the ability of LMD to simultaneously increase systemic blood pressure, decrease blood viscosity and disaggregate red blood cells in the microcirculation.
犬失血量达计算血容量的40%时，体循环血压降至约50 mmHg。这伴随着肝脏总血流量下降至正常水平的约60%。输注低分子右旋糖酐（LMD）或生理盐水，其容量相当于所取出血量的1/7，可增加肝脏总血流量。这种增加在LMD组更为显著，可能是由于LMD能够同时升高体循环血压、降低血液黏度并使微循环中的红细胞解聚。
