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巨大外生性平滑肌瘤母细胞瘤致大量腹腔内出血

Massive intraperitoneal hemorrhage caused by a giant exogastric leiomyoblastoma.

作者信息

Karatzas G, Kouraklis G, Delladetsima J, Glinavou A, Karayiannacos P

机构信息

Second Department of Propedeutic Surgery, Faculty of Medicine, School of Health Science, University of Athens, Greece.

出版信息

Surg Today. 1998;28(3):293-5. doi: 10.1007/s005950050124.

Abstract

Leiomyoblastomas account for a small percentage of smooth muscle tumors of the stomach. Intraperitoneal bleeding is an unusual and unexpected presenting sign. We herein present a 43-year-old woman who was urgently operated on due to signs of collapse. A large hemorrhagic mass measuring 25 x 18 x 15 cm was found arising from the greater curvature of the stomach. A histologic examination demonstrated rounded and spindle cells, and rare mitoses were also seen. Although the number of mitoses was small, the lesion was nevertheless felt to be consistent with malignant leiomyoblastoma because of its large size. Three years later the patient is doing well with no evidence of tumor recurrence. We conclude that intraperitoneal bleeding due to leiomyoblastoma of the gastrointestinal tract is an extremely rare phenomenon and has been described only in a few reports, and only one other previous case presented with signs of collapse.

摘要

平滑肌瘤在胃平滑肌肿瘤中占比小。腹腔内出血是一种不常见且出乎意料的表现体征。我们在此报告一名43岁女性,因出现虚脱体征而紧急接受手术。在胃大弯处发现一个大小为25×18×15厘米的巨大出血性肿块。组织学检查显示有圆形和梭形细胞,也可见罕见的核分裂象。尽管核分裂象数量少,但由于肿块体积大,该病变仍被认为符合恶性平滑肌瘤。三年后患者情况良好,无肿瘤复发迹象。我们得出结论,胃肠道平滑肌瘤导致的腹腔内出血是一种极其罕见的现象,仅在少数报告中有描述,且之前仅有另一例出现虚脱体征。

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