Matsui H, Hirano N, Sakaguchi Y
Department of Orthopaedic Surgery, Toyama Medical and Pharmaceutical University, Faculty of Medicine, Sugitani, Japan.
Eur Spine J. 1998;7(1):50-4. doi: 10.1007/s005860050027.
The purpose of the study was to evaluate the characteristics of patients with vertebral osteomyelitis who were treated by anterior debridement and interbody fusion. Thirty-eight patients with vertebral osteomyelitis, who were treated between 1980 and 1993, were analyzed in terms of age at the occurrence of disease, duration of disease, type of onset symptoms, radiological type of vertebral destruction, species of pathogen, and surgical result. Thirty-one out of 38 patients (82%) were more than 40 years of age. The patients with severe vertebral destruction were significantly older than those with mild vertebral destruction. Vertebral destruction in the thoracic spine was significantly more severe than that in the lumbar spine. Staphylococcus aureus was identified in only six patients (32% of organism-determined cases). In the present patients who required anterior debridement and bone grafting for this disease, the prognosis was quite good after anterior interbody fusion in conjunction with antibiotics therapy.
本研究的目的是评估接受前路清创和椎间融合术治疗的脊椎骨髓炎患者的特征。对1980年至1993年间接受治疗的38例脊椎骨髓炎患者，从发病年龄、病程、起病症状类型、椎体破坏的放射学类型、病原体种类及手术结果等方面进行分析。38例患者中有31例（82%）年龄超过40岁。椎体严重破坏的患者明显比轻度破坏的患者年龄大。胸椎椎体破坏明显比腰椎严重。仅在6例患者中鉴定出金黄色葡萄球菌（占病原体确定病例的32%）。在目前因该病需要前路清创和植骨的患者中，前路椎间融合联合抗生素治疗后的预后相当良好。
