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下肢肉瘤保肢手术中可扩张假体的应用

Expanding prostheses in conservative surgery for lower limb sarcoma.

作者信息

Delepine G, Delepine N, Desbois J C, Goutallier D

机构信息

Service d'Orthopédie, Hôpital Henri Mondor, Créteil, France.

出版信息

Int Orthop. 1998;22(1):27-31. doi: 10.1007/s002640050202.

Abstract

Conservative resection of bone sarcoma in the lower limbs in children is very likely to be followed by a progressive problem of leg length inequality resulting from removal of the growth cartilage. To overcome this we have been using an expanding prosthesis and we report our experiences during the period 1985-1996. The prostheses are made of titanium and comprise 3 parts: an articular component, an expanding mechanism, and tibial and femoral stems. The degree of possible lengthening of the prostheses is virtually unlimited, and they can be inserted in children of 5 or more years of age. We report the use of 28 prostheses in patients aged from 5 to 18 years, of which 4 were tibial, 5 total femur, and 16 distal femur. There were 6 Ewing's sarcoma, 21 osteosarcoma, and 1 synovial sarcoma. The average follow-up was for 5 years. Five patients died from their disease, and 21 benefited from an average lengthening of 2.6 cm (range: 2 mm-120 mm). Using the Société Européenne des Tumeurs Osseouses (EMSOS) criteria, the functional results were excellent or very good in 16, fair in 7 and bad in 5. Five patients developed an infection; one required amputation and the others received a new expanding prosthesis. We conclude that an expanding prosthesis is an excellent alternative to amputation in young children. However, the risk of infection associated with repeat surgery has led us to develop a prosthesis which can be lengthened externally, without the need for reopening the wound.

摘要

儿童下肢骨肉瘤的保守性切除很可能会因生长软骨的切除而导致渐进性的腿长不等问题。为克服这一问题,我们一直在使用一种可延长假体,并报告我们在1985年至1996年期间的经验。这些假体由钛制成,包括三个部分:一个关节部件、一个延长机构以及胫骨干和股骨干。假体的可能延长程度实际上是无限的,并且可以植入5岁及以上的儿童体内。我们报告了在5至18岁患者中使用的28个假体,其中4个用于胫骨,5个用于全股骨,16个用于股骨远端。有6例尤文肉瘤、21例骨肉瘤和1例滑膜肉瘤。平均随访时间为5年。5例患者死于疾病,21例患者平均延长了2.6厘米(范围:2毫米至120毫米)。根据欧洲骨肿瘤学会(EMSOS)标准,16例患者的功能结果为优或良,7例为中,5例为差。5例患者发生感染;1例需要截肢,其他患者接受了新的可延长假体。我们得出结论,对于幼儿来说,可延长假体是截肢的一种极佳替代方案。然而,与再次手术相关的感染风险促使我们研发一种无需再次打开伤口即可在体外延长的假体。

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