Hoekstra M O
Afd. Kinderlongziekten, Academisch Ziekenhuis, Beatrix Kinderkliniek, Groningen.
Ned Tijdschr Geneeskd. 1997 Nov 15;141(46):2223-9.
The diagnosis of 'asthma' is still based on anamnesis, physical examination and lung function tests. Supplementary examinations (laboratory or roentgen) are carried out only if indicated. Most young children with recurrent periods of wheezing and coughing prove not to develop asthma in the long run. Oral medication no longer has a place in the treatment of asthma, since inhalation medication is now possible at all ages, among other things because of the current availability of new nozzle attachments. Every child with asthma should have a short-acting beta 2-agonist at hand. Furthermore, inhaled corticosteroids are the maintenance drug of choice in children with moderate or severe asthma. Systemic effects may occur with every inhaled corticosteroid, even with dosages usual for children, but these are rarely relevant. Cromones nowadays play a very limited part. Long-acting beta 2-agonists are indicated in children whose asthma cannot be controlled with standard doses of inhaled corticosteroids. In the prevention of allergic asthma of childhood, prescription of the allergen-tight mattress cover plays a main part. The physician has an important task in discouraging (passive) smoking. Young children who, in spite of treatment with inhaled corticosteroids, have recurrent episodes of wheezing and coughing. and children requiring high doses of inhaled corticosteroids (over 400 micrograms beclomethasone/budesonide or 250 micrograms fluticasone) should be referred to a paediatrician. The asthma nurse has an important task in instructing and advising the asthmatic child and its parents. Self-management programmes may be of great psychological value for the patient and his environment.
“哮喘”的诊断仍基于病史、体格检查和肺功能测试。仅在有指征时才进行补充检查(实验室检查或影像学检查)。大多数反复出现喘息和咳嗽的幼儿最终证明不会发展为哮喘。口服药物在哮喘治疗中已不再适用,因为现在各个年龄段都可以使用吸入药物,这尤其得益于目前新型喷头附件的 availability。每个患有哮喘的儿童都应备有短效β2激动剂。此外,吸入性糖皮质激素是中度或重度哮喘儿童的首选维持药物。每种吸入性糖皮质激素都可能产生全身效应,即使是儿童常用剂量,但这些效应很少具有相关性。色酮类药物如今的作用非常有限。长效β2激动剂适用于那些使用标准剂量吸入性糖皮质激素无法控制哮喘的儿童。在预防儿童过敏性哮喘方面,开具防过敏原床垫套起着主要作用。医生在劝阻(被动)吸烟方面负有重要任务。尽管使用了吸入性糖皮质激素仍反复出现喘息和咳嗽的幼儿,以及需要高剂量吸入性糖皮质激素(超过400微克倍氯米松/布地奈德或250微克氟替卡松)的儿童应转诊至儿科医生处。哮喘护士在指导和建议哮喘儿童及其父母方面负有重要任务。自我管理计划对患者及其周围环境可能具有很大的心理价值。 (注:原文中“current availability of new nozzle attachments”的“availability”翻译为“可用性”较生硬,这里暂保留英文未翻译,可根据上下文灵活调整更通顺的表述。)