Jausseran J M, Ferdani M, Houel F, Rudondy P, Rezzi J, Reggi M, Padovani R
Service de Chirurgie Cardio-Vasculaire, Hôpital Saint-Joseph, Marseille.
J Mal Vasc. 1998 Feb;23(1):7-12.
A prospective study was done in 100 patients operated on for a stenosis of the carotid artery by the eversion endarterectomy method of Van Maele (section-eversion-anastomosis) between January 1994 and August 1995. Ten patients were operated on bilaterally (thus, 110 procedures). The distribution of the patients was as follows 81 males and 19 females, mean age 71 years. Clinically, 50 patients were asymptomatic, 44 stage I, 2 stage II and 4 stage III. Arteriography of these patients showed 42 stenoses greater than or equal to 90%, 56 stenoses between 70 and 90% and 12 ulcerated plaques (according to the ESCT measurement standards). Concerning the supra-aortic vessels, 24 lesions of the vertebral-subclavian branches and 21 lesions of the intra-cerebral vessels were observed. Five endarterectomies out of the 110 (5.4%) could not be performed by this eversion method because of the immediate poor technical result before angiography. At the end of the procedure digital angiography was performed for all the patients who underwent an eversion endarterectomy (105 cases). Six images of the internal carotid artery presenting stenoses less than 30% were observed at the level of the implantation site. Two narrow stenoses of the distal part of the endarterectomy made the interposition of a PTFE graft necessary in 20% of the cases, a secondary procedure was necessary after the peri-operative angiography 2 implantations of PTFE in the internal carotid artery, 8 additional endarterectomies of the external carotid artery, 11 infiltrations with Papaverine. The immediate post-operative results were 1 death after hemiplegia, 1 hemiplegia with sequelae (mortality/morbidity approximately 2%, i.e. 2/103 eversions), 3 regressive hemipareses. Angiographic follow-ups after 1 year were performed on 100 out of 110 operated carotid arteries. With regard to the internal carotid artery, 4 patients showed a stenosis less than 30%, 1 patient a 50% stenosis, 1 patient a pre-occlusive stenosis making an operation with the interposition of a PTFE graft necessary (restenosis rate after one year 2%). All the patients followed after one year remained asymptomatic. Eversion endarterectomy is possible for the majority of the atheromatous stenoses of the carotid artery (5.4% were not possible for technical reasons). We find this method not appropriate when a shunt must be placed. Immediate results are comparable to those of classical surgical endarterectomy with or without patching. The restenosis rate at 1 year in our series is 2%. This technique provides an excellent anatomic result by peri-operative angiography and can especially be adapted to stenoses with excess of length of the carotid artery.
1994年1月至1995年8月期间,对100例采用范梅勒外翻式内膜切除术(分段-外翻-吻合术)治疗颈动脉狭窄的患者进行了一项前瞻性研究。10例患者接受了双侧手术(因此,共进行了110次手术)。患者分布如下:男性81例,女性19例,平均年龄71岁。临床上,50例患者无症状,44例为I期,2例为II期,4例为III期。这些患者的动脉造影显示,42处狭窄大于或等于90%,56处狭窄在70%至90%之间,12处溃疡斑块(根据欧洲血管外科学会测量标准)。关于主动脉弓血管,观察到24处椎动脉-锁骨下分支病变和21处脑内血管病变。在110次手术中,有5次(5.4%)因血管造影前技术效果不佳而无法采用这种外翻方法进行内膜切除术。手术结束时,对所有接受外翻式内膜切除术的患者(105例)进行了数字血管造影。在植入部位水平观察到6例颈内动脉狭窄小于30%的图像。内膜切除术远端的2处狭窄使20%的病例有必要植入聚四氟乙烯移植物,围手术期血管造影后需要进行二次手术,2次在颈内动脉植入聚四氟乙烯,8次额外的颈外动脉内膜切除术,11次罂粟碱浸润。术后即刻结果为1例偏瘫后死亡,1例偏瘫有后遗症(死亡率/发病率约为2%,即2/103次外翻手术),3例进行性偏瘫。对110根接受手术的颈动脉中的100根进行了1年后的血管造影随访。关于颈内动脉,4例患者显示狭窄小于30%,1例患者狭窄50%,1例患者为闭塞前狭窄,需要进行植入聚四氟乙烯移植物的手术(1年后再狭窄率为2%)。所有随访1年的患者均无症状。对于大多数颈动脉粥样硬化狭窄,外翻式内膜切除术是可行的(5.4%因技术原因无法进行)。我们发现当必须放置分流器时,这种方法不合适。即刻结果与经典手术内膜切除术(有无补片)的结果相当。我们系列中1年的再狭窄率为2%。通过围手术期血管造影,该技术可提供出色的解剖学结果,尤其适用于颈动脉长度过长的狭窄。