Urry R L, Thompson J, Cockett A T
Fertil Steril. 1976 Aug;27(8):945-50. doi: 10.1016/s0015-0282(16)42023-6.
Twelve adult, bilaterally vasectomized dogs were used to compare two different procedures for reuniting the severed vas deferens. Approximately 5 months postvasectomy six dogs had vasovasostomies utilizing Silastic stents and the vasa deferentia of six additional dogs were rejoined with intravasal chromic stents. Ejaculates were subsequently obtained at 2-week intervals and evaluated for sperm count, motility, viability, and seminal ion concentrations. All of the dogs in which Silastic had been utilized as the stent had sperm reappear in the ejaculate, whereas only 40% of the dogs in which chromic catgut had been utilized had reappearance of spermatozoa. The over-all quality of the ejaculate was also better in the animals in which Silastic had been utilized. Testicular and epididymal histology was normal in most dogs of both groups, but three of the dogs with chromic stents in which the anastomosis had not been a success had abnormal histology, with reduced numbers of spermatocytes, spermatids, and spermatozoa. The data suggest that Silastic stents are better than chromic stents for vas reanastomosis. They also suggest that some dog testes react negatively to vasectomy and do not recover by 1 year postvasectomy when vas patency is not reversed.
选用12只成年双侧输精管结扎犬,比较两种不同的输精管断端吻合方法。输精管结扎术后约5个月,6只犬采用硅橡胶支架进行输精管吻合术,另外6只犬的输精管采用血管内铬制支架重新连接。随后每隔2周采集射精样本,评估精子数量、活力、存活率和精液离子浓度。所有使用硅橡胶作为支架的犬射精样本中重新出现了精子,而使用铬制肠线作为支架的犬中只有40%重新出现了精子。使用硅橡胶的动物射精样本的总体质量也更好。两组大多数犬的睾丸和附睾组织学检查正常,但3只使用铬制支架且吻合未成功的犬组织学异常,精母细胞、精子细胞和精子数量减少。数据表明,在输精管再吻合术中,硅橡胶支架优于铬制支架。数据还表明,一些犬的睾丸对输精管结扎反应消极,在输精管通畅未恢复的情况下,输精管结扎术后1年仍未恢复。