Effect of hydrocortisone 17-butyrate on the percutaneous absorption of antibiotics.
作者信息
Simon N, Dobozy A
出版信息
Dermatologica. 1976;152 Suppl 1:215-9. doi: 10.1159/000257892.
PMID:955236
Abstract
Abrption of antibiotics from combined preparations containing oxytetracycline, chlortetracycline, doxycycline or gentamicin and hydrocortisone 17-butyrate into the skin of rats was examined. The penetration of antibiotics from the ointment into the skin was inhibited by 0.2% hydrocortisone 17-butyrate to a significant degree. It is suggested that this effect of hydrocortisone 17-butyrate is the consequence of its vasoconstrictor action.
摘要
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