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[再生大鼠肝细胞S期和G2期染色体放射敏感性的比较]

[Comparison of the radiosensitivity of chromosomes during the S and G2 periods in regenerating rat liver cells].

作者信息

Polishchuk A M, Aksenovich T I, Mamaeva O A

出版信息

Genetika. 1976;12(4):35-40.

PMID:955412
Abstract

Radiosensitivity of chromosomes at S and G2 periods was studied by means of autoradiography technique in cells or regenerating liver of rats treated with X-rays at the doses of 150 and 300 r. The experiments were made so that the interval between irradiation and mitosis in S and G2 cells was equal. The results have shown that under the experimental conditions there are significant differences in the yield of chromosome aberrations between the labelled and intact cells. This withnesses for the existence of differences in radiosensitivity of chromosomes at different periods of mitotic cycle.

摘要

采用放射自显影技术,研究了用150伦琴和300伦琴剂量的X射线照射大鼠再生肝或细胞后,处于S期和G2期染色体的放射敏感性。实验设计使得S期和G2期细胞照射与有丝分裂之间的间隔相等。结果表明,在实验条件下,标记细胞与完整细胞之间染色体畸变率存在显著差异。这证明有丝分裂周期不同时期染色体的放射敏感性存在差异。

相似文献

1
[Comparison of the radiosensitivity of chromosomes during the S and G2 periods in regenerating rat liver cells].[再生大鼠肝细胞S期和G2期染色体放射敏感性的比较]
Genetika. 1976;12(4):35-40.
2
[Yield of chromosome aberrations induced by x-irradiation in regenerating rat liver cells at different periods of the generation cycle].[不同细胞周期阶段再生大鼠肝细胞经X射线照射诱导的染色体畸变率]
Tsitologiia. 1977 Mar;19(3):367-72.
3
[Change in the radiosensitivity of chromosomes during the S-period in cells of regenerating rat liver].[再生大鼠肝细胞S期染色体放射敏感性的变化]
Genetika. 1977;13(7):1194-1201.
4
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Biull Eksp Biol Med. 1981 Mar;91(3):359-61.
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6
[Duration of the mitotic cycle and radiosensitivity of chromosomes in human lymphocytes].
Radiobiologiia. 1988 Mar-Apr;28(2):187-9.
7
[Effect of x-radiation on DNA synthesis and cell population kinetics in regenerating rat liver. II. Cell irradiation in S and G2 periods].
Tsitologiia. 1973 Jun;15(6):712-21.
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The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells. I. Initial damage.同步化X射线照射的L5178Y细胞中DNA和染色体损伤与存活的关系。I. 初始损伤。
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Study of the nature of damages to chromosomes of the nuclei of amphibian leukocytes after their irradiation in various phases of the mitotic cycle. I. Irradiation in the G2 phase.两栖类白细胞细胞核在有丝分裂周期各阶段受照射后染色体损伤性质的研究。I. G2期照射。
Sov Genet. 1974 May 1;8(3):321-7.
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Cell proliferation in the regenerating liver and the effect of prior continuous irradiation.
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