梨火疫病菌通过Hrp（III型分泌）途径分泌DspE，一种致病因子和功能性AvrE同源物。
Erwinia amylovora secretes DspE, a pathogenicity factor and functional AvrE homolog, through the Hrp (type III secretion) pathway.
作者信息
Bogdanove A J, Bauer D W, Beer S V
机构信息
Department of Plant Pathology, Cornell University, Ithaca, New York 14853, USA.
出版信息
J Bacteriol. 1998 Apr;180(8):2244-7. doi: 10.1128/JB.180.8.2244-2247.1998.
Abstract
Erwinia amylovora was shown to secrete DspE, a pathogenicity factor of 198 kDa and a functional homolog of AvrE of Pseudomonas syringae pv. tomato. DspE was identified among the supernatant proteins isolated from cultures grown in an hrp gene-inducing minimal medium by immunodetection with a DspE-specific antiserum. Secretion required an intact Hrp pathway.
摘要
已证明梨火疫病菌能分泌DspE，这是一种分子量为198 kDa的致病因子，也是丁香假单胞菌番茄致病变种AvrE的功能同源物。通过用DspE特异性抗血清进行免疫检测，在hrp基因诱导的基本培养基中培养的菌株所分离出的上清蛋白中鉴定出了DspE。分泌需要完整的Hrp途径。
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